Some advice needed!
I was diagnosed 18months ago at the age of 50 with CLL plus 17p deletion and have been on Idelalisib since last October (CALIBRE trial) I have tolerated the Idelalisib very well and have seen all my symptoms vanish leaving me feeling 100% healthy and my blood counts next to normal.
My consultant at The Christie has now raised the idea of having a mini-stem cell transplant using cord blood. He hasn't sugar coated the real outcomes of being either a cure, part cure with graft v host disease or death.
I know keeping with the Idelalisib runs the risk of Richter's tranformation and eventual failure of it.
I know there are several trials ongoing with combination of the newer agents but until my trial fails I am disqualified.
I really could do with some second opinions from UK professionals if anyone knows?