Given we currently have a few members going through bone marrow transplants, this review article in CancerNetwork by Mark-Alexander Schwarzbich, MD, Fabienne McClanahan, MD, PhD, and John Gribben, MD, DSc should be of interest:
You may need (free) registration to view the article.
Note you may find the article rather confronting; stem cell transplants are rarely done for CLL and for good reasons. You are a better candidate for a transplant if you have been diagnosed at a (relatively) young age with CLL.
Some of the topics covered:
- Markers Predictive of Successful HSCT in CLL
- Management of Relapse After HSCT
- Alternative Immunochemotherapy-Based Treatment Options for Patients With TP53 Abnormalities
- Novel Treatment Options in CLL
- Which Patients Should Be Offered HSCT in the Era of Novel Agents?
(Check out table 2, which gives an overview of the advantages and disadvantages on Novel Agents and Haematopoietic Stem Cell Transplants)
Photo: Sometimes it's necessary for a new fence post or a new bone marrow...