Thanks for this Brian, my initial reaction was that it seemed unfair that the better option was not being offered to 50 per cent of those on the trial. I was molified somewhat at the crossover option, but still wonder whether there is a yet unmentioned drug that has passed initial trials that could be used in such a trial.
Guess phase 3 is more of a proving trial.. If so perhaps we can look forward to a reasonably early release.
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