Obinutuzumab and venetoclax in relapsed cll,

[Rameshchag]

My father got diagnosed cll october 2009,was on wait and watch till mid 2014,then given R-bendamustine and was on remission till october 2016,then started ibrutinib in 2016 and stopped ibrutinib in mid 2018,in 2020 end due to fast multiplication of tlc and enlarged spleen and lymphnodes our doc suggested o+v and started day 1 with 100mg of obinutuzumab and day to at 900mg,day 8 with 1000mg of obinutuzumab and day 15 again with 1000mg obinutuzumab,and introduced veneto ramp up 20mg dose for one week on day 31 along with 1000mg obinutuzumab,platelets are 10 and hb hover around 7gm,tlc is 2,he needs infusion of platelets and PRbC every other day,bone marrow aspiration shows diffused infiltration of lymphocytes,

Just want to know how long it will take platelets and haemoglobin to bounce back if anybody has gone through similar situation.

Thanks