Antibiotics and Liver Disease - British Liver Trust

British Liver Trust

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Antibiotics and Liver Disease

Taffypaul profile image
9 Replies

For nearly 3 years since being diagnosed with cirrhosis , I have been very healthy, my bloods are excellent, my fibro still very high 40kpa and I've not taken one pain killers or tablet. but I'm good and healthy except now, when I have a chest infection , my young doctor prescribed me amoxicillin 5 day course then 1 hour later messaged me to say she has changed the prescription to Erythromycin , I'm reluctant to take either to be honest especially the later.

Has anybody to taken antibiotics ? What did they give you or any general thoughts, appreciate you are not doctors just interested

Thank you Paul.

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Taffypaul
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9 Replies
NieceByMarriage profile image
NieceByMarriage

I have asthma and COPD so I would never myself risk a chest infection getting worse. Having had pneumonia earlier this year (while on drugs for Hep C) I can tell you that it is not an experience I would recommend. The antibiotics did not cause me any problems I know of, liver-wise, and I ended up in hospital on IV antibiotics, so I had plenty! I assume your doctor knows your liver condition but if you are reluctant to take the drugs I would suggest you check back with her. My personal view is that the drugs may be the lesser of two evils. Hope you feel better soon.

AyrshireK profile image
AyrshireK

If you need antibiotics to clear an infection then you need them or else you risk serious deterioration in both the chest infection but also potentially your liver. Infection can quickly destabilize a cirrhotic liver.

My hubby is on Penicillin for life as he has a non-viable spleen. Been on them since June 2014 and continues now even post transplant.

Katie

Trewargas profile image
Trewargas

Hi Taffypaul.

I had a UTI early this year and I was prescribed Nitrofurantoin by my GP.

Obviously a different antibiotic to yourself.

The UTI symptons cleared up successfully within a several days, but anecdotally after about 4/5 days of the Nitrofurantoin I started feeling generally really very unwell. This horible malase persisted for several weeks only very slowly abating.

After about 10 days of feeling awful, I contacted the BLT helpline for any appropriate advice.

They informed me that Nitrofurantoin was one of the "known" medications that in ideal situations is better to be avoided if you have cirrhosis.

They suggested I let my surgery know.

So I have now learned a lesson when being asked to start new medications by the Dr.

Always check if it's OK for a cirrhotic patient with my particular history.

On a personal note, I also have had pneumonia in the past, and it hospitalised me for a week. It's not to be recomended.

Best wishes which ever way you decide to go with regards to your antibiotics.

Richard.

glander2405 profile image
glander2405

I had oral surgery and liver dr said Z pack, seemed to be ok. I had strep throat years ago and was prescribed cefdinir and that messed me up badly resulting in chronic right sided pain that got slightly better when gall bladder was removed.

Ericabear profile image
Ericabear

Hi, my husband takes Rifixamin antibiotics every day prescribed by his liver consultant following his Hepatic Encephalopathy. He is, touch wood, doing well. 🙂

Ewife profile image
Ewife

Hello, my husband likewise didnt take a single tablet other than what was prescribed for his cirrhosis. Over the 4 years, he had various infections and took antibiotics when prescribed. We found he had a spike in bilirubin both when he had antibiotics but also when he had a virus, covid, head cold etc where he had no antibiotics. It usually settled down again within a few months - but it was the food poisoning which saw his final deterioration.....and he had no medication for this - so proves that infection can be as bad as antibiotics for the liver.Trust your Dr but if you are still worried, check with a liver nurse.

Atb

Ewife

Aotea2012 profile image
Aotea2012

I’ve always taken the drugs doctors prescribe. Liver disease makes you particularly susceptible to infection and it’s important to take antibiotics to help clear those infection. There are very high stakes as the body doesn’t clear infections as well with an underperforming liver and chest infection have a nasty habit of getting more serious. You even risk sepsis. If you are really worried, most surgeries now have dedicated pharmacists if you can’t get hold of the GP. If you are really struggling to get hold of someone in the surgery, speak to whoever dispensed the prescription to check it.

Milser profile image
Milser

Back in Jan 23 I had a liver biopsy that bled and had a coil embolism to stop it. One week later I was back in hospital with an abscess on liver and I had five days of IV antibiotics and then home with six weeks of tablet antibiotics. My liver specialist team prescribed those.

JAM44 profile image
JAM44

Hi, none of us like having to take extra tablets that our livers need to process, so I don’t rust to take them, but I have had to take antibiotics a few times since being diagnosed. My main issue with them is that I often just have significantly less energy and don’t feel great whilst on them, feels like my liver is using more of its effort to process them and fight the infection, leaving the normal day to day functions of running of my body a bit under supported!! However I generally get back to normal quite soon after stopping them. Hoping all goes well for you.

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