Steatosis vs Steatohepatitis on Fibroscan.

[Qwertrew]

I'm curious if fibroscan can be used to distinguish between steatosis and steatohepatitis. I have not been able to find any info online, and wonder if anyone might have any insight/personal anecdote/scholarly article that might allude to an answer? Thank you.

[MINTVCX]

Basically it cannot. Steatohepatitis can only be confirmed for sure by liver biopsy. Of cours there are some blood tests that can also tell something.

[Qwertrew in reply to MINTVCX]

Thank you! Do you know if steatohepatitis could be commonly present with normal (4.5) kpa and enzyme levels if the CAP score is 312?

[AyrshireK]

No, that would be stretching fibroscan's capabilities - it can give a fat content score (CAP) and a liver density score (kPa) but even with the kPa score it can't actually tell whether the tissue is actually fibrotic or whether the tissue is inflamed (hepatitis). So, there is no way it can give any sort of reading as to steatohepatitis. Like MINTVCX states bloods and a biopsy are probably the only way to establish if there is ongoing steatohepatitis/liver inflammation.

Katie

[Qwertrew in reply to AyrshireK]

Ok. That is curious. My most recent fibroscan/lft test yielded 312 CAP and 4.5 kpa and enzymes within range, i know the CAP is really high, so I was curious if there is a chance of steatohepatitis instead of merely steatosis. I read that with steatohepatitis, the liver is inflamed which might cause falsely high kpa scores so wondering if my "normal" kpa might mean I am less likely to have it.

[AyrshireK in reply to Qwertrew]

If your inflammation markers (ALT, GGT etc.) are normal then it points to a likeliehood of no ongoing hepatitis.

[Qwertrew in reply to AyrshireK]

Thank you, that makes me feel better!