Birmingham trial

[eekk]

Anyone tried the clinical trial radio therapy at Birmingham for hcc ?

[DeniB]

No, but I'm having really good response with Immunotherapy trial for Pembrolizumab for HCC. I'm stage 4, l was given 6 mths! I'm now stable 3 yrs later. If you're eligible have a search for it. I travel to Liverpool every three weeks. It's changed and saved my life.

[eekk in reply to DeniB]

What is that? A tablet or drip or radio? Thanks

[DeniB in reply to eekk]

Half hour infusion/drip every three weeks

[KT60]

What is the trial at birmingham ny husband has untreatable hcc. The trial at liverpool has ended now. I live in liverpool and did enquire about it after seeing denib post a while back karen

[eekk in reply to KT60]

I am finding out today and will post back

[KT60 in reply to eekk]

Ok thanks karen

[KT60]

Hi did you find out anything about the trial karen

[eekk in reply to KT60]

It is every other day -radio trial for 14 days

[eekk in reply to eekk]

Or there is the chemotherapy tablets

[KT60]

What is the radio trial is it radio therapy, is it a new treatment, how is it given, is it only birmingham that is doing the trial, sorry for the questions its just that i would ask at liverpool if its available there. Are the chemotherapy tablets sorafenitab. They wont do anything for my husband they said its not the tumours its the liver thats the problem he is decompensated this happened after he had ablation last year karen

[eekk in reply to KT60]

It is only Birmingham and London currently offering the trial.Liverpool can refer but I would have thought they would have already mentioned it if suitable but you can double check.

It is a radiotherapy trial given as an outpatient every other day.I do not know how it is administered.

The tablets are Sorefenib

[eekk in reply to KT60]

It is new it is only a trial so no outcomes are known as yet as to if it works or not

[KT60]

Ok thank you will ask them its worth a try. I take it you are under birmingham, we had to go there to see if my husband could have transplant but cos he had heart attack 2 yrs ago was refused but it seems like an excellent hospital. Karen

[KT60]

Sorry for so many questions how did you find out about the trial if you dont mind me asking

[eekk]

Not at Birmingham but you can be referred from the one you are with if suitable.Heard from consultant

[KT60]

Do you think you will give it a try. What hospitsl are you with, my husband is at aintree hospital liverpool he used to be with royal in liverpool but wasnt happy with consultant so changed but still no better as regards hcc treatment

[KT60]

Hi eekk when you mentioned radio therapy i thought it might have been sabr (stereotactic ablative therapy) and it is.

I asked the liver specialist nurse about it she confirmed it is sabr, i have read about it before i think it has been used in other countries for hcc and other cancers. There is information about it on the macmillan website in case you want to read about it. Karen

[eekk]

We decided not to do it.

[Melita17]

This is very interesting. My brother has cirrhosis of the liver and has just been told that the oncologist need not see him anymore because there is nothing he can do. When he asked about liver transplant he was told he was 'too far gone'. He took Sorafenib for 2 weeks but the side effects were horrendous. My brother got every side effect you can get with it. What else can he do? Will another oncologist put him on this infusion/drip if he went to a different hospital? Any help will be gratefully received.

[eekk in reply to Melita17]

Most here have the HCC coupled with cirrhosis. At this point all that is offered is clinical trials or natural therapies