I had a liver transplant in 2006 due to PSC. It has been a fantastic success. Last year however my Neutrafil level fell to "undetectable" for a couple of months but spontaneously recovered. All during this time i felt perfectly well except for a bit of angulitus. Docs could find no reason for the suppression. Even a bone marrow biopsy could offer no explanation. Best thoughts were that tacrolimus was the cause (a rare but acknowledged risk). Before a trial switch to cyclosporin could be completed however the neutrafil level recovered.
Back in September my Neutrafil level was suppressed below normal again but had improved a month later. Docs again want to switch me to cyclosporin. My research however indicates that neutrafil suppression is an acknowledged risk with that medication too.
Has anyone else suffered neutrafil suppression with either tacrolimus or cyclosporin? Any thoughts on why neutrafil levels can become suppressed but recover without intervention?
Thanks in advance.