Hi, i am 48 yrs operated for Rt DCIS: MASTECTOMY with Sentinel node biopsy done on 6th May. HPE report states 5x5x5.5 cm hard nodular mass. All margins are free. Extensive intraductal carcinoma nuclear grade3, solid, comedo & cribriform types. Multiple foci of microinvasive carcinoma grade III. single focus of invasive breast CA 0.2 cm. Lymphovascular emboli or perineural invasion not seen. 2 nodes negative.
Overlying skin shows focal paget's disease.
ER/ PR Negative
CerbB2 positive score 3+
I gather i am T1a Stage 1
My dilemma is whether i should take chemotherapy or no since there are no guidelines in NCCN. kindly guide me Dr Rohit & Dr Sumeet