Zoladex and mood swings: Hello everyone... - My Breast Cancer ...

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Zoladex and mood swings

Janaphi32 profile image
26 Replies

Hello everyone! Im 32 on hormonal therapy with tamoxifen and zoladex and about one week before my shot i have anxiety depression aches in my knees crying all the time and most of the time i dont know why. I don't want to go out and see friends and have negative and confused thoughts that float into my head. It is scaring me that I feel so bad mentally wise. I've been having zoladex injections for the last 1 year and wonder if it is because of this? Anyone else experiencing the same side effects? Thanks!

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Janaphi32 profile image
Janaphi32
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26 Replies
Louisejr profile image
Louisejr

Hi there

I could be writing what you have put. I'm a week away from my next injection and feeling all over the place. I've actually just come up to bed to have 5 mins on my own as I'm feeling very low and emotional. Literally every thing hurts, even my fingers and thumbs.

It definitely ebbs and flows in between injections. I am only 6 months in and was hoping things would improve but it is definitely difficult. I am on Letrozole too - and was wondering which was making me feel worse but I guess as both have similar side effects it is probably both.

I have started bathing with Magnesium Flakes and it does seem to be helping. I also drink plenty of water which also seems to help too, when I feel like I am right now.

I don't know about you, but I always feel better knowing that someone else is experiencing the same things and means I'm not nuts or imagining it all.

Sending you hugs 🤗

Louise xx

Janaphi32 profile image
Janaphi32 in reply toLouisejr

It definitely helps knowing that someone else is experiencing this symptoms and that im not going nuts :p i tried epsom salt i cant say it helps much. I think that is very low estrogen that has to do with this and nothing much can be made. Are you on hormonal therapy for breast cancer too? Thanks a lot louise!! Xxxx

Janaphi32 profile image
Janaphi32 in reply toJanaphi32

What is letrozole for?

Louisejr profile image
Louisejr in reply toJanaphi32

Sorry missed this - letrozole is an alternative to Tamoxifen it is an inhibitor xx

Janaphi32 profile image
Janaphi32 in reply toLouisejr

Im going for a walk now. Hope it will make me feel better :) take care xxx

Louisejr profile image
Louisejr in reply toJanaphi32

My other half is out today - so going to have a pamper day 👍enjoy your walk xx

Janaphi32 profile image
Janaphi32 in reply toLouisejr

Thanks u 2!! Xxx

Louisejr profile image
Louisejr in reply toJanaphi32

Hi, yes I am on Letrozole. I had a lumpectomy and sentinel node removal last October, followed by radiotherapy. I think I thought that after the op and RT I would be back to normal but definitely underestimated the side effects of the drugs. Most of the time I feel like I am in a bubble, and it is difficult to explain to people who have not gone through this how you actually feel. Having no hormones does affect you mentally.

My cousin who is 2 years down this road from me suggested Magnesium, and I def can feel a difference.

I don't know about you but in some way knowing that you are not imagining all of this and that these side effects are real goes a little way to feeling better about it all.

Take care

Louise 😘

Janaphi32 profile image
Janaphi32 in reply toLouisejr

I know and feel its all about the hormones thats why im saying we cant do much about it. I feel like im a different person for some days. And like these days when i think about it a lot it gets me very low. Our mind confuses us easily. :( i also went to a homeopathy doctor and discovered im low in vitamin d propably from chemotherapy so im taking also vitamin d and cod liver oil to cleanse it. Im on antidepressants too for 4 months but i think its not needed. Its all games of the mind prior to my ' period' which i dont have

Janaphi32 profile image
Janaphi32 in reply toLouisejr

Btw magnesium does the same thing with epsom salt. It indeed relaxes u a bit :) Hugs to u!

Louisejr profile image
Louisejr in reply toJanaphi32

Will give them a try.

Hugs to you too 🤗😘

Debs1962 profile image
Debs1962

Sound s like Louise knows what you are going through which I think really helps to not feel alone, what injections are you on? And what are they for?

I hope you can get some relief from the side effects, and maybe try the suggestions from Louise xx

Louisejr profile image
Louisejr in reply toDebs1962

Hi Debs

The Zoladex basically puts your ovaries to sleep to stop you producing oestrogen if you are pre menopause. I am 52 but when they did blood tests they said I was not near menopause as my oestrogen levels were very high. I think it is more usually given to ladies that are much younger than me and does not affect their fertility. As I am older and my child bearing days long gone I am going to ask about ovary removal as I am struggling with the side effects.

Louise 😘

Debs1962 profile image
Debs1962 in reply toLouisejr

Oh I see now, I was 52 when diagnosed now 54 but was already in the menopause so just on letrozole, sounds like you may benefit from op to remove ovaries xx

Janaphi32 profile image
Janaphi32 in reply toDebs1962

Hi debs. The zoladex injection is for stopping my period and lowering the estrogen as a preventive measure of cancer to reoccur. It definitely helps to not feel alone. Thanks! Xxx

Debs1962 profile image
Debs1962

That is the great thing about this site, you are never alone xx

Artemis-angel profile image
Artemis-angel

I too take zoladex and get days when I feel down and emotional which is not like me at all. I find it's either just before my next injection or around the time of my next monthly cycle.

Janaphi32 profile image
Janaphi32 in reply toArtemis-angel

How old are you? Sending u hugs! We are gonna get through this!

Artemis-angel profile image
Artemis-angel in reply toJanaphi32

52 I've been taken zoladex about 6 years hopefully coming off it soon

Louisejr profile image
Louisejr in reply toArtemis-angel

I'm supposed to have it for 2 years - counting down on Thursday it will be six so 18 to go 🙄xx

Janaphi32 profile image
Janaphi32 in reply toLouisejr

Im on zoladex for 5 years. We ll see how it goes :/

Janaphi32 profile image
Janaphi32 in reply toArtemis-angel

U ve been through a lot. Hope your problems end soon :) xxx

Louisejr profile image
Louisejr in reply toJanaphi32

Thank you - both my Mum and Cousin have had BC and are both survivors and as they keep telling me you've just got to get through it 😘

Lana0322 profile image
Lana0322

I am 29 and I had breast cancer 2 years ago and I went throw it all I had a bilateral mastectomy the did hard core chemo now I'm on zoladex and letrozole for hormone therapy I'm glad I found this page by googling lol I haven't had any side effects and November will be 2 years I've been on this medicine but just had my shot Thurs and probably sat I started getting knee pain sharp pains threw my left knee so is that from the shot? I've never had it happen before so I don't know should I ask my doctor?

janaphi profile image
janaphi in reply toLana0322

i have the same thing too! and i kinda feel my knees hurt and makes me wonder if it has something to do with osteoporosis. im 32 btw

Lana0322 profile image
Lana0322 in reply tojanaphi

I'm not sure my doctor said I was to young to have to worry about it but I don't know ill have to say something to her it just started

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