Bisoprolol cause low mood & weight gain? - British Heart Fou...

British Heart Foundation

56,150 members34,909 posts

Bisoprolol cause low mood & weight gain?

Staffylover67 profile image
9 Replies

Hi everyone,

I’m taking bisoprolol, was on 1.25 mg, been increased to 2.5mg for ILVT.

I know it’s still quiet a small dose, but seem to be gaining weight, having more of an appetite and my mood seems to of dipped these last few weeks?

I take fluoxetine 20mg for depression & anxiety, just trying to work out if it’s the bisoprolol or more emotional?

Any thoughts on this, much appreciated 👍

Written by
Staffylover67 profile image
Staffylover67
To view profiles and participate in discussions please or .
Read more about...
9 Replies
AmatureKnitter profile image
AmatureKnitter

Bisoprolol gives me fatigue and brain fog. I gain weight and can't be bothered with anything. Most I can take is 1.25/day, I periodically take a higher dose if needed, but reduce it quickly to avoid being zombified. Luckily I don't need it often now, but when first prescribed I was titrated to 7.5/day and after a few weeks it was obvious the side effects were too much and that was stressful.

I did notice the side effects improved after about 4 months, I started to adjust and find ways around them. But I'll only ever take the absolute minimum dose needed to keep my arrhythmia in check.

I can see if you're prone to low mood you can think it's making it worse, but from talking to thousands (17.5k) of others in the Arrhythmia FB group, I'd suggest it's fatigue and low energy and the stress that causes that's the culprit, not a direct worsening of a mental health issue. It's all linked though.

Have you tried anything to help?

devonian186 profile image
devonian186

Its quite normal to put on weight during the winter period. We seem to go into some sort of semi hibernation mode, store fat and eat more carb heavy foods than we may during the warmer times. The weather and dark evenings are well known problems and is called SAD.

From my health diary in the winter of 2022/3 and 2023/4 I noted that sometimes the weather has caused me to be at the "end of my resilience" what with cold, rain, darkness etc and my exercise levels measured by my steps will drop from 70/80000 a week to 40/50,000.

It was less noticeable in the past as we would go ski-ing a couple of times during the winter which gave us something to look forward to, more exercise and more sunshine that lifted the mood

MoretonCross profile image
MoretonCross in reply todevonian186

I really can't agree with your first two sentences, I think you're speaking for yourself there. It certainly doesn't apply to me, however SAD is a thing for sure.

devonian186 profile image
devonian186 in reply toMoretonCross

Many People put on weight, often during the run up to Christmas and beyond. The New Year is the favourite time to start diets and exercising. Obviously not everyone but quite a few do, and I admire your restraint if you don't

ASD46 profile image
ASD46

Hi Staffy, I started on Bisoprolol early Autumn, only a low dose, but I’d say I’ve put on weight since taking it and I do find and increased tiredness/fatigue. I guess it’s designed to slow down the heart to a degree so it’s not a huge surprise but it’s something I’m keeping an eye on.

DWizza profile image
DWizza

How much weight have you put on ? Just after Christmas?

I’m on 1.25mg bisoprolol, reduced from 3.75 over a year ago. I’ve lost weight and pretty much plateaued.Consultant said I can come Off bisoprolol , I’m trying to cut it in half for a couple of weeks (fiddly even with a pill cutter). If anything I have more of an appetite but that really could be down to being much more active. Also on aspirin, pantaprazole and 10mg Rosuvastatin post nstemi and quadruple bypass July 2023

BC4ever profile image
BC4ever

I take 1.25mg of Bisoprolol (reduced from 5mg because it was making me exhausted). I still felt tired, so my Cardiac Nurse told me to take it before I went to bed. This helps - so much better. Not had any problems with gaining weight, in fact the opposite - lost three stone!

fishonabike profile image
fishonabike

Bisoprolol ( a beta blocker) can affect the way your body processes glucose as well as steadying your pulse and slowing you generally - these can make you more likely to put on weight and feel weary

There are alternative treatment you could ask your doctor about. Often, in IK the cheapest option is tried first but if it does not suit you you can ask about alternatives.

Breesha profile image
Breesha

I am the Bisopropol fan, Biso is a lifesaver, I have been on 10 mgs a day since first prescribed over 10 yrs ago upped to 12.5 at one point ,

I am 80, still work from home and have plenty of energy , Dapha is the pill that made me put on weight, but too busy with charity work to feel depressed.

See if you can help part time in a charity shop, the antics of the customers will soon cheer you up. …

Not what you're looking for?

You may also like...

Bisoprolol and weight gain

I have been on bisoprolol 5mg daily since Sept last year after two events of tachycardia in close...
daisy2311 profile image

bisoprolol and mood

I’ve been taking bisoprolol now for nearly two years. In the past few months I’ve noticed I am...
TheBoys profile image

Bisoprolol weight gain.

Hi. Has anybody got any advice please regarding losing weight caused by my taking 10mg a day for...

Bisoprolol and weight gain ?

Greetings all, I haven’t spoke for sometime on here so I hope your all coping well. The main...
highburyted profile image

Bisoprolol

Does anyone who has it is withdrawing from Bisoprolol know if drawing from 0.01 to 0.1mg if the...

Moderation team

See all
HUModerator profile image
HUModeratorAdministrator
Luke_BHF profile image
Luke_BHFPartner
Will_BHF profile image
Will_BHFPartner

Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them.

Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked.