Bisoprolol : Good morning. Hope... - British Heart Fou...

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Elvis4 profile image

Good morning. Hope everyone is well. I take 2.5mg Bisoprolol in the morning and 1.25 mg Bisoprolol in the evening. I've run out of my 2.5 mg but if I take two 1 25mg it will be the same as 2.5 mg of bisoprolol. I'm sure it will but just looking for confirmation. Thank you ☺️

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41 Replies

Well, I have done this and still here to tell the tale.Can't see why it would not be effective.I hasten to add I am quite timid re. messing about with meds. but did not hesitate on this one.

1.25 + 1.25 = 2.5

100% fine, just as breaking a 2.5mg tablet in half will give you 2 X 1.25 tablets, if you ever run out of 1.25’s

Always best to look for confirmation from Your gp instead of a forum like this as we are not allowed to give advice. It may be that its ok but please get a gp advice before self medicating

Gaz_chops profile image
Gaz_chops in reply to

Sorry, but on this occasion there is absolutely no need to bother a GP!

If reassurance is really needed then speak to your pharmacist.

Gaz_chops profile image
Gaz_chops in reply to Gaz_chops

Just to clarify, they are not changing dosage, merely asking if 2x1.25mg is the same as a 2.5mg, which it is.

in reply to Gaz_chops

This is why we ate not allowed to give advice on this forum.what feels right for one person osmotic necessarily the correct thing to do. I stand by what I said. Best to check.eith professionals

Gaz_chops profile image
Gaz_chops in reply to

Absolutely not necessary, but like I said if they really really need reassurance then speak to a pharmacist.

If they called for a GP appointment for this, the receptionist would refuse & tell them it was fine as it was the same dosage.

in reply to Gaz_chops

Of course 1.25+1.25=2.50 and I'm.sure it absolutely fine. I've done it myself many times, but always with gp knowledge and approval . We are very lucky here if we phone to ask for gp.advice someone will phone back straight away Must be quite bad where you are if a teceptionist refused to give you a gp appointment

I wouldn't ask fir an appointment I would ask.for advice. You are right about the pharmacist option though. They will be able to advise also.

Gaz_chops profile image
Gaz_chops in reply to

You would really waste a GP's time asking if it is ok to take 2X 1.25mg tablets as you had run out of 2.5mg tablets, wow

in reply to Gaz_chops

Clearly you see it as a waste of time. Bless you

Gaz_chops profile image
Gaz_chops in reply to

No, I know it is a waste of a GP's time, end of conversation.

in reply to Gaz_chops

Wow!! End of conversation because you say so?? Oh you sweetheart. You have the most special evening.

MikeBB profile image
MikeBB in reply to

Really? You’re wrong and they’re not - and you can’t even accept the advice gracefully? I’d be fascinated to know though how taking two tablets of half the prescribed medication is any different from one tablet, of the prescribed medication. It’s not as though the prescription has changed, and it’s not ‘advice’ is it?

Palpman profile image
Palpman in reply to

You must be joking. Right?

My GP & Cadrio NP have advised me to double up on various medications during the process of working out which is the best balance to manage my Afib and post OHS management.

I have split tablets in half to get smaller doses, double up on smaller doses to make a larger dose and so on.

Always done it with GP knowledge because they are the ones who have to authorise early repeat of prescriptions because one dosage wil run out before the system says you should need some more.

in reply to Brand


I do this frequently although in reverse, as I am on 7.5mg and take my 2.5's as a pill in pocket so have run out of them occasionally. I use a pill cutter to cut them. Doc was fine with this. So doubling is no problem. It is the same dose. In fact when Pharmacy's run out of specific dose's they will double up on a lower dose if they have stock for the same medicine.

You could also get an emergency prescription direct from your Pharmacist without going to your GP, as long as they have your normal prescription it will not be an issue.

It's a bit like asking the pharmacist re- warfarin dosage. I take 6mg per day, now should I take it 2×3, 6×1, 5+1, 3+(3×1). 6 is 6 whichever way.

[Doora's not a doctor disclaimer here]

I have 150mg Aspirin tablets. I only need 75mg so if I break one in half will both still be Aspirin or must I make a fool of myself and ask my GP?

As a Pharmacy Technician I would say yes to your question. This happens frequently in pharmacy as in your case having run out,also because of stock and supply shortage and changing of dosage (strength). If you run out again, contact your pharmacy explain what's happened and they can give you an 'urgent supply. Hope this helps.

For you to be sure ask the pharmacist they will tell you give them a call.

Yep 2 of the smaller ones makes one dose of the larger..

Yes that’s fine, doesn’t matter how you take it as long as the same mg

Hi. You may get asked why you need to re order a little early. As long as you explain there shouldn't be an issue. You can usually do this with tablets as long as one dose isn't normal and one perhaps slow release. If in any doubt check with pharmacist who are the experts on drugs.

Hi Elvis4. Had a HA early August and had some ongoing angina issues. I have been on 7.5mg (2.5 in morning and 5 in evening) for over a year now I think. Rather than get mixed up with 5mg and 2.5.g tabs I take 2x2.5 at night. My GP suggested this. This is my experience and not my advice...😉

Yes I do the same have done for years when I get low good luck kwagmire??

Should be ok

I do it all the time as I take 13 different meds twice a day and occasionally run out of 1 particular dosage, but have an alternative larger or smaller dose drug from when I was being trialled. There is absolutely no harm in mixing/matching/ dividing one particular med providing it's maintaining the correct dose. For us ( those who have been on these drugs for years) it's a simple and obvious solution to the problem. However, if one is new to the drug, nervous or sceptical, it always pays to check with the g.p. They will NOT ridicule you, just reassure you.

Just call your local pharmacist and ask them though I can't see a problem apart from you running out of the others..You can ask them if they Meds Manage so they can take over ordering for you so this doesn't happen. This is an important medication, trust me, and managing your supply is important.

Pharmacist here. You can double up, no worries. However you need to get a supply of 2.5mg as you will be running out of the 1.25mg as well by taking three in a day You will get hopelessly out of synch - I’ve seen this so many times - so get your new prescription sorted ASAP. You can get an emergency supply from your pharmacy in the U.K. but that’ll will be subtracted from your prescription when it arrives from GP and in a month or so you will be running out again.

While I was in hospital my prescription for this drug was changed from 1.25 to 2.5. Rather than waste the tablets I already had, the pharmacist Re-stickered them so that the instructions said to take 2 rather than 1 at a time.

My dosage is 2.5 mg, and it is prescribed as 2 x1.25mg tablets, even though I take them both together in the morning. So definitely no problem.

Yes it will be

Ok Elvis, I seem to be getting battered here , especially by some people that love the limelight. If both your meds are the same then you should be ok halving them. If one is slow release and the other isn't then that is different. Im not sure why I am being singled out here as others have suggested you get advice from a professional too. Perhaps too much time on their hands or nothing to watch on TV??

Gaz_chops profile image
Gaz_chops in reply to

Probably because the ‘advice’ you gave originally was bad ‘advice’.

GP practices triage calls, calls of this nature would simply clog up an already overloaded system, the caller would be advised it was ok or be directed to a pharmacist.

in reply to Gaz_chops

Ooooh hi there Gaz_ chops!!! I thought YOU had decided to end the conversation? You wee devil you! You just can't help yourself can you!!?? You reminded me of someone who.just HAS TO touch wet paint even though the sign says not to!! Little imp!! I bet you have a little book full of your opinions on every possible scenario, then you just chose them accordingly? Remembering, of course, that only yours are right. You dear wee soul.

Gaz_chops profile image
Gaz_chops in reply to

I ended the discussion as to whether or not it was appropriate to waste a GP appointment, this is not my opinion it is a fact.

When someone gives incorrect advice I feel obliged to make sure the OP isn’t misled.

I should of just reported your post ☺️ but then the OP wouldn’t realise it was bad advice.

in reply to Gaz_chops

Thank you so so much, I am forever in your debt You are so wise.

Gaz_chops profile image
Gaz_chops in reply to

You are most welcome 😀

I'm on the same dose, and my cardio and pharmacist advised me to break a 2.5 into two 1.25 pieces as they were spacing out my doses to prevent side effects. So, I can say unequivocably that it's totally fine.

Just to throw something else into this discussion, my understanding is that breaking tablets into half and getting equal amounts of medication in each half depends upon the actual medication itself. There is no guarantee that the medication is equally dispersed in a tablet. You have to refer to the information leaflet or ask your pharmacist or GP if it is ok to do this. If you look at Bisoprolol the 2.5 mg are scored and designed to be split into two parts each of 1.25 mg and the 3.75 mg are actually scored to be split into 3 if necessary each of 1.25mg or even split into 2 with one part equal to 2.5 mg and the other equal to 1.25mg. The point is that it is important to check before splitting tablets. However, I have done what you are trying to do many times with different tablets - that is to take two lower dose ones to equal a larger dose - without any problems.

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