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Eplerenone Inspra

Taraharp profile image
14 Replies

Hi all I have been taking Entresto high dose 97/103 for low EF and LBBB for 3 months now and have been advised to take the Eplerenone as well as it is supposed to help the heart muscle. A lot of the comments online seem to be negative. Does anyone else have experiences of this drug and does it help at all? what side effects do other folks have? I have no oedema and therefore do not require a diuretic at this stage.

Thank you

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Taraharp profile image
Taraharp
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14 Replies
Prada47 profile image
Prada47

Hello Tara

I see you are on a high dose of Entresto currently I am on 49/51 twice a day going to 97/ 103 as soon as my Heart Nurse comes back to work after being on the sick !!!

I have been taking 25mg Eplerenone for a couple of years from what I know it helps control Blood Pressure and is a Mild Diuretic. I was switched from Spirolactone after some problem with boobs ( I am a Male )

I have no problems with Eplerenone or with Entresto other Meds are Aspirin 75mg, Bisoprolol 7.5mg Pravastatin 10mg and Omeprazole 20mg

My EF is low 40s and like you have an element of LBBB

If you don't mind how long have you had HF and what's your EF My only symptom is Breathless when doing some pretty routine work and Low Blood pressure.

Best Regards

Taraharp profile image
Taraharp in reply toPrada47

Hi,

Thank you for your reply.

I have had heart failure since May 2018 following a stomach bug when the Lbbb was discovered as well. My EF was 37% I was on ramipril for a year but that did not seem to work as my ef returned to 37 having increased to 55%. I am glad you have no side effects from the Eplerenone. Has your EF improved.? I am due another echo in a month or so. This will be number 5 in less than. 2 years! I have no side effects from the Entresto either.

Best wishes

Prada47 profile image
Prada47 in reply toTaraharp

Hi

My next Echo is May/June prior to my annual appointment with Cardiologist that's when I will have been on Entresto for a full year !!

Regards

Taraharp profile image
Taraharp in reply toPrada47

Hope it goes well

Prada47 profile image
Prada47 in reply toTaraharp

Thanks

Prada47 profile image
Prada47

Hi TRST

Is the reason for coming off entresto the Alzheimer Issue?? I never got to ask my Heart Nurse she has been off sick !! so it's 6 months since I have seen anyone. Have appointment for 5th Match and I will ask then.

Regards

I will ask on the Pumping Marvellous site which is an HF forum and see if anyone has information. Done

Lezzers profile image
Lezzers

My husband may be taking Entresto soon, it's been a bit of a wonder drug for heart failure, If you can tolerate it. Can I ask why you want to come off it?

Prada47 profile image
Prada47 in reply toLezzers

HI Leslie

This is a link provided by TRST when we discussed this in an earlier post ncbi.nlm.nih.gov/pmc/articl...

Lezzers profile image
Lezzers in reply toPrada47

Thanks Frank, unfortunately the link doesn't work! Would be interested in having a look at it if you wouldn't mind trying again.

Prada47 profile image
Prada47 in reply toLezzers

Try this Leslie

ncbi.nlm.nih.gov/pmc/articl...

Lezzers profile image
Lezzers in reply toPrada47

Thank you

Prada47 profile image
Prada47 in reply toLezzers

It's a good evaluation but at almost 73 I think I will take my chance Alzhiemers V Heart Failure at least with Alzheimers you may not even be aware your dying!!! Not sure if I should be LOL or Breaking Down and Crying !!! Crazy World We Live In LOL

Lezzers profile image
Lezzers in reply toPrada47

I do agree, most meds are a trade off in one way or another. I'll read the link, talk it through with Kevin & then we'll discuss it with his cardiologist.

Fortunately there's not history of alzheimers I'm his family so that may be a plus.

Lezzers profile image
Lezzers

Thank you

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