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Bisoprolol-night or day?

Caitlyn6 profile image
120 Replies

I have been prescribed Bisoprolol 1.25mg and Cardiologist said to take at night. I have read in the leaflet it says to take in the morning. Do I just continue nighttime? Not due to see cardiologist again for a while. Did anyone else find they have the hands of a 100 year old whilst taking beta blockers or is that just me? Also consultant said heart rate on exercising should be 120 max. I love running but it shoots to 158 with a gentle jog. Should I avoid jogging? Cycling is fine and heart rate 120. I have hypertension, diabetes, MS and some moderate atheroma. I am 49. I was put on beta blockers for some tachycardia on exertion. I also have a reduced lung function (70%). Cause as yet unknown. CT scan in a week. Thanks for any advice re beta blockers. ❤️

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120 Replies
Urssy profile image
Urssy

Hey.

I take mine (2.5) in the morning. That's what I was told by the hospital. I wonder if it's because I take atrovastatin at night? Not sure.

Haven't noticed any side affects but have only been on them a few weeks.

Caitlyn6 profile image
Caitlyn6 in reply to Urssy

I also take atorvastatin 40mg at night

Urssy profile image
Urssy in reply to Caitlyn6

Yeah mine's 40. I wonder if you can take the other morning or night then? I haven't had any affects...be interesting to see when others are talking it.

Caitlyn6 profile image
Caitlyn6 in reply to Urssy

I understand cholesterol tablet is better at night as that is when the liver produces cholesterol but it can be taken other times

MichaelJH profile image
MichaelJHHeart Star in reply to Caitlyn6

Atorvastatin is somewhat more effective taken at night. My understanding is that if your levels are in (and stay in) range (total 4 or below, LDL 2 or below) morning is fine.

Rosei profile image
Rosei in reply to Caitlyn6

I take mine in the morning.

HectorandBoris profile image
HectorandBoris in reply to Urssy

I take atorvastatin at night and Bisoprolol in the morning.

healyhcare profile image
healyhcare in reply to HectorandBoris

I am on Atrovastatin 80mg. and take at night with Remipril 1.25mg. and Bisoprolol 1.25mg in the morning with Ticagrelor 90mg. Ticagrelor is to stop after taking it for a year. not felt any side effect so far.

Gaz4545 profile image
Gaz4545 in reply to Urssy

Ditto altho I take 5mg of Bisoprolol :)

Pippa1234 profile image
Pippa1234 in reply to Urssy

You might be one of the lucky ones

tollkkotooe profile image
tollkkotooe in reply to Urssy

Bisoprolol without a prescription - onlinecheappills.com/bisopr... I have no words for how amazing bisoprolol is. I'm a 22 year old male with Severe Anxiety, Panic Disorder, Hypertension and Tachychardia. I was prescribed 2.5mg of Bisoprolol and it didn't bring any significant change to anything, my BP reading was always on 130-150/85-110 never lower than that and my heartbeat rate was always past 80. So I decided to up the dose to 5mg/day, I was shocked that my BP reading was 121/78 today (15 minutes after taking the 5mg dose). Not to mention that my anxiety was reduced too, following my slowed heartbeat rate. This drug is quite the lifesaver, also on another case if you experience any Panic Attack just gulp down 5mg of Bisoprolol and you will be fine and better in 30 minutes. This works so well for me.

Shoshov profile image
Shoshov

hi mollypet. i was put on 2.5 mg last wk and was told to take at night too. but i’m very symptomatic to lots of medications but so far iv been fine. good luck❤️shiona

in reply to Shoshov

I have been placed on bisoprolol 5mg to take at night. I have not started yet because of possible outcome and lack of emergency services here in Nigeria

MichaelJH profile image
MichaelJHHeart Star

Hello and welcome to the forum! I have Type I diabetes, PAD (peripherial arterial disease) and CVD (had a quadruple bypass last year). Fortunately the answer to your question is quite simple. You are on the lowest dose of Bisoprolol. When first starting on it some people feel dizzy but this usually settles in a few days, so people are started in the evening. If you notice no symptoms move to the morning to derive most benefit. Its half life means its effect is tailing off at the end of the day. The day time when you are up and about is when you need its effect most.

Caitlyn6 profile image
Caitlyn6 in reply to MichaelJH

Thank you Michael. Would I gradually swap to morning- i.e currently take at 10pm. Change to 6pm,2pm,10am?

MichaelJH profile image
MichaelJHHeart Star in reply to Caitlyn6

This is an area where people become vague. Ideally you should not go without medication for over 24 hours. As you are on such a low dose you should be fine taking it in the evening and then the next morning.

Caitlyn6 profile image
Caitlyn6 in reply to MichaelJH

Thank you.

Caitlyn6 profile image
Caitlyn6 in reply to MichaelJH

Yes this is my worry. I was on propanalol 10mg for two weeks then gp decided to taper me off over a two week period but I had terrible rebound. So I'm wary of overdosing or underdosing by accident.

MichaelJH profile image
MichaelJHHeart Star in reply to Caitlyn6

IMHO (I am not medically qualified but a physicist) Bisoprolol is the better drug as it is more modern and has a better half life (10 - 12 hours rather than 5 - 7). It is more expensive though.

willsie01 profile image
willsie01 in reply to MichaelJH

Hi, why is Bisoprolol prescribed relative to heart issues?

MichaelJH profile image
MichaelJHHeart Star in reply to willsie01

It has two main effects; reducing BP and HR thus improving the heart's efficiency. It also has benefits in some types of heart failure.

These days the trend is to use multiple medication as it seems more efficient than a large dose of a single medication, e.g. an ACE inhibitor is often combined with a beta blockers.

Pippa1234 profile image
Pippa1234 in reply to MichaelJH

Its the cheapest beta blocker on the market. That's why its prescribed first, that information came from my doctor

MichaelJH profile image
MichaelJHHeart Star in reply to Pippa1234

Interesting - I was told Atenolol was cheaper but only by a £1 or £2 per month. Allegedly Bisoprolol is the more effective drug.

Shar28 profile image
Shar28

Hi, my husband splits his Bisoprolol into two doses, one mid morning after his other meds and the other at bedtime. His Cardiologist is happy with that.

He was also advised to exercise so that his heart rate is no more then 80% of the normal maximum for his age. Ie 220-age x 80%.

I think that’s fairly standard advice but his condition is different from yours so you might want to check with your Cardiologist/GP/BHF nurse helpline.

All the best.

Caitlyn6 profile image
Caitlyn6 in reply to Shar28

Thank you. That's helpful

Grandad4 profile image
Grandad4

I take mine in the morning and statin/ clopidogrel at night

I was advised by cardiologist and hospital pharmacist to take Bisoprolol in morning and statins at night Like Shar28 rehab nurses said Hr should be 220-age x 80%

in reply to

Seems to me the safer option

Purpletara profile image
Purpletara

I take 1.25 of bisoprolol in the morning at breakfast and 1.25 at about 7 at night. This works well for me. I was having more AF episodes during the night so doctor split the dose and so far everything is much better.

Spring_melody profile image
Spring_melody in reply to Purpletara

What is AF?Thanks.

Purpletara profile image
Purpletara in reply to Spring_melody

Atrial fibrillation where the heart beats erratically. I’m no expert on this and I’m sure others on this forum could explain better but I think it’s when the hearts electrical system goes haywire. Hope this helps.

Leshowell profile image
Leshowell

Hi I was taking mine in the morning I'm on 10mg ,but found I was feeling tired in the afternoons so my gp said try taking it at night, so I now take it about 6pm with my lisinopril 5mg . Seems to work for me.

Prada47 profile image
Prada47

Hello

Heart Nurse and Cardiologist have been trying to get my dose of Bisoprolol optimised over the past few weeks. I have been changing between 7.5 and 10mg of Bisoprolol and switched from Morning to Night back to Morning. The reason for the change was at Night I was going down to as low as 22 bpm and I was getting pauses in my heart beat !! This was all monitored by a Holter and by a Telemetry/recording system whilst spending 24hrs in Hospital. Term used was Nocturnal Bradycardia. I do take a Statin at night along with Entresto.

So the regime at the moment is Morning, Bisoprolol, Aspirin, Omeprazole, Isosorbide.

Mid Morning Furosemide, Eplerenone, Entresto.

Night is 2nd Entresto. With my medication I just follow what I have been told and take it as prescribed !!

Regards

in reply to Prada47

Omeprazole is believed to cause weakness in the bones. Please take note

tigerjuz86 profile image
tigerjuz86 in reply to Prada47

Hi I hope your still around I’m on a lower dose 2.5 which I take also on a night ,,

Keep waking up with my heart rate beating fast ,, keeps dropping to 53 that’s after I’ve had a good 5 mins rest I didn’t feel breathless like gasping for breath but felt short of breath kind of thing hard to explain

Did this happen to you like how did you know it was dipping that low I’ve had a ecg but came back normal

Are you on omperazole since taking the biso as my belly done nothing but bloat and been given lansprazole for gastritis

Hope you have managed to get your heart rate under control x

Prada47 profile image
Prada47 in reply to tigerjuz86

Hello I am still around lol Bisoprolol is now 7.5mg and my heart rate can be between 45 and 60 but it is steady around those two figures. My Heart Nurse was checking my pulse and it paused for a couple of seconds so back on the Holter Monitor the low was 33 bpm in the night (resting )

Being short of breath and breathless are two different things ! my Nurse again said when did this shortness of breath start again my answer was it hasn't she just said well it has now. So she could see I was short of breath I think you learn to manage it breathing to a pattern which disguises that you are short of breath, if you can understand what I mean !!

Vaccinated Twice to Stay Safe

tigerjuz86 profile image
tigerjuz86 in reply to Prada47

Hi just with it being 2 years ago thought oh please lol

I’m still on 2.5 they want to adjust but not sure if it’s my gastritis or my bisoprolol causing me feel off my blood pressure seems stable just when I’m in pain or feel funny goes up :(

Aw god that’s low do you not feel weird with it that low and did you find the higher the dose the lower the heart rate

Oh have they said why the pause happens ,, omg that’s so low 33 I’m panicking at 53 but I don’t know what it goes to when I’m sleeping

So you didn’t feel yourself short of breath is that maybe coz you haven’t focused and noticed

I think I get what you mean like you’ve learnt to breath a different way to what you used to before

May I ask a silly question probably a simple thing ,, how did you manage to take your bisoprolol in a morning from the night as my bp sort of knows it’s due hour o 2 before so don’t want go to bed with it high kinda thing ,, like do u take a double dose or change times slowly forwards or backwards

Sorry for all questions I’m just wary on change at the moment

But thank you sooo much for getting back to me really appreciate it :) x

Pippa1234 profile image
Pippa1234

Bisoprolol will cause you to be unable to exercise, feel tired a d lethargic plus. Dont put up with it, get it changed. Its easy for docs to prescribe these meds they need to try them!! The side effects of bisoprolol are horrible. I came off them and am now on calcium channel blockers which do the same job. My doc said they prescribe bisoprolol first because its the cheapest!!!!! Good luck

Wendersyay profile image
Wendersyay in reply to Pippa1234

I agree! I felt complete exhaustion for months then got taken off bisoprolol and within a week I was so much better! I was taking it at night on advice of doctor as I take ramipril in morning. I take statin at night. 🙂

2468abcmuk profile image
2468abcmuk in reply to Pippa1234

I was on verapamil for over 30 years & my

Cardiologist said bisoprolo is a far safer drug to take it was not available 30 years ago & verapamil has much more serious side effects

Gladwyn profile image
Gladwyn in reply to 2468abcmuk

I was on verapamil for many years until my heart attack 4 years ago when it was stopped. The only side effect of the verapamil I was aware of was water retention. Lol I'm still retaining water probably a side effect of one or other of the meds I'm on now .

in reply to Pippa1234

Exactly what I am very reluctant to start this medication, plus you can not stop when you have started

Thank God for a forum like this one

tigerjuz86 profile image
tigerjuz86 in reply to Pippa1234

Hi I’m 2 years late but may I ask which side effects did you have with bisoprolol please Im unsure if my feeling not right is them

If any what side effects on the calcium channel blockers please ,, which one are you on and was a instant switch or ween off

Sorry for all questions just losing hope as I asked my gp to reduce or split my dose as think too much as my sleep is awful n heart rate drops low which don’t like the lightheadedness

Thank you x

I take all my medicine including 5mg Bisoprolol and 80mg Atorvastatin in the morning when I wake up. I am always tired in the afternoon. After reading the replies I might try taking them at night.

Ramblingross profile image
Ramblingross in reply to

I take Bisoprolol 5mg at night and also 80 mg Atorvastatin at night..both together...no problems up to now..

House28 profile image
House28

I also take them I'm on 2mg in the morning used to be at night, now changed to morning as it can affect all other meds x

Dragon1973 profile image
Dragon1973

Hi. I take mine in the morning. Doubled it to 2.5 and it seems to have settled

dickielex profile image
dickielex

I have taken it in the morning for many years on medical advice. I also take a statin at night.

SelstonCanary profile image
SelstonCanary

I take half of a 1.25 tablet in the morning, doctor halved it as my heart rate was very low. I asked him about running and what heart rate to aim for and he told me not to run as I need to protect my heart! Found that a bit surprising but it just shows that advice is very much dependent on a range of factors.

Caitlyn6 profile image
Caitlyn6 in reply to SelstonCanary

Gosh u don't expect to be told not to run.

neto1964 profile image
neto1964 in reply to SelstonCanary

How u donit as poll so small

SelstonCanary profile image
SelstonCanary in reply to neto1964

Bought a pill splitter, makes a nice neat job!

neto1964 profile image
neto1964 in reply to SelstonCanary

So u took 1.25 mgs divided in 2 doses right ?

SelstonCanary profile image
SelstonCanary in reply to neto1964

No, just half of a 1.25 tablet per day. But of course that’s just for my particular circumstances, everyone is different so always go with what your medical professional says.

Munroedundee1 profile image
Munroedundee1 in reply to SelstonCanary

Is it ok to half the 1.25 entericoated tablet? I need to do same.

SelstonCanary profile image
SelstonCanary in reply to Munroedundee1

Only if that’s what your gp or cardiologist recommends.

tigerjuz86 profile image
tigerjuz86 in reply to SelstonCanary

Hi I’m glad I’ve seen this post and your still come on here what did your heart rate drop to please , I’m on 2.5

My heart rate has been low since been on 53 my lowest to date makes me feel lightheaded told my dr and asked to half or split it but wouldn’t find it worser when I’m sleeping as it wakes me up ,, he won’t do that but gave me a ecg and came back normal

I didn’t know went lower then 1.25 bf did you get withdrawal effects doing it if he won’t do it I feel it makes me anxious so will be adamant and tell him I need lower dose if it has helped you hopefully it can me too

Was you prescribed for high blood pressure as I thought running would help the heart I push as hard as I can to get it pumping or is that why feel rubbish

Sorri all questions I’m having a mind explosion my partner at work so come to this forum to let my worries out I’m so sorry

Hope you are well and hope t lower dose helped x

SelstonCanary profile image
SelstonCanary in reply to tigerjuz86

Hi, still well thanks.

My resting rate is in the low 40s with blood pressure consistently normal so that’s why they lowered my dose. I actually find it quite difficult to raise my heart rate significantly when exercising which I think reinforces the decision to put me on such a low dosage.

Didn’t have any withdrawal symptoms at all. Like I said originally, this works for me but of course we are all unique so go with whatever your health professional recommends but let them know if you have any concerns.

Keep well!

tigerjuz86 profile image
tigerjuz86 in reply to SelstonCanary

Hi I am so pleased to hear that you are well :)

Oh do you feel okay when it’s at that rate or has yours always being low

Oh did you not ween yourself off just broke in half and was fine I’d be scared I’d be doing crumb by crumb

Yea that is true we are all human but all different and yeah I will be letting them know my concerns :)

Thank you for getting back in touch Keep well and take care too :) x

BigT2013 profile image
BigT2013

I take mine morning.

Some doctors say to take at night because it avoids some of the side effects.

For example Bisoprolol can make u feel tired and exhausted.

Night time at some stage u would be in bed or asleep.

U may also get swollen ankles but in the evening or night u may have feet up or would be lying down.

The Bisoprolol is still in your system doing its job just helping with some side effects it can take 3 weeks plus for it to be completely out of your system.

Also Bisoprolol is at its most potent in the blood 2hours after taking which is when the worst of side effects would be if any.

It's usually well tolerated.

Hope this helps

SelstonCanary profile image
SelstonCanary

Yes, I did find it a bit odd but he did say to keep exercising but just to watch the intensity. He did also remind me that I’m knocking 60 as well!

Caitlyn6 profile image
Caitlyn6 in reply to SelstonCanary

I will continue with low intensity then, although it's abit boring

timestudy.co.uk

I take mine in the morning, I have been taking it for 20 years!

I am also part of this study & they have groups of patients, some of whom take it in the morning & some in the evening. I was asked to take mine in the morning [but also with my Consultants approval]

I believe that the latest thinking, is that taking the anti-hypertensives in the evening has a better outcome for the patients

I think they are currently collating all the information & it will eventually be published.

Caitlyn6 profile image
Caitlyn6 in reply to

Thanks for sharing that

wiltsgirl profile image
wiltsgirl

Hi Mollypet and welcome. After my bypass a year ago I was put on 3.75mg of beta blocker which I took in the morning as advised by the hospital. I soon realised it caused my BP to go so low that I felt completely exhausted and dizzy. My Dr then reduced the dose and now I don't take it at all. I was told by my cardiologist that taking it for the first year protects the heart from the surgery. I now take aspirin, Ramipril (1.25mg) and statin (20mg). Good luck with things xx

Caitlyn6 profile image
Caitlyn6 in reply to wiltsgirl

Thank u

mariancolyer profile image
mariancolyer

Taking Bisoprolol at night for two years- 2.5 mg - I'm in heart failure - Dilated cardiomyopathy - and despite my heart being at 40% I feel very well. My sleep pattern is not great but I manage my life well so I feel that taking it at night is not negative.

There are prescription helplines so possibly worth investigating them and asking a few questions if you still feel uncertain.

in reply to mariancolyer

Could you please advise me on how to get a link to the prescription health lines?

jacquirg profile image
jacquirg

Hi

I have a genetic heart problem and was prescribed 10mg per day, which I take in the morning. I am always cold. I decided a few months ago to reduce the quantity as I was exhausted all day from the tablets. I now take 2.5mg and some magnesium supplements and I have a lot more energy. You must do what’s right for you. Only you can monitor how these tablets are making you feel. Doctors prescribe them but we all react differently. Try taking them in the morning and evening and see what works. Good luck

Caitlyn6 profile image
Caitlyn6 in reply to jacquirg

Many thanks

in reply to jacquirg

I took the triple calm magnesium supplements and my palpitations became worse

tigerjuz86 profile image
tigerjuz86 in reply to jacquirg

Hi did you lower the dose yourself I have passed my concerns to my gp as feel same and it drops my hr bit low then my liking as causes me go lightheaded ,, what are these magnesium supplements I’ve had people tell me on this forum about them but I look on Amazon and so many different ones I haven’t a clue ,,

I’m so glad you feel better how did you reduce off them please x

LHDLondon profile image
LHDLondon

I take both my bisoprolol and atorvastatin at night, reason being that bisoprolol can make one dizzy. Ive been on this regime for over a year with no bad effects.

Dsd123 profile image
Dsd123

Hi my dad has recently prescribed beta blockers (bisprolol and ramipril). He was feeling dizzy so he's been advised to take them before bed time so he's lay flat and at no risk of fainting. Hope that helps?

Qualipop profile image
Qualipop

I started taking bisopralol at night but had terrible hallucinations. I would wake up seeing 3 foot long black worms painted all over the walls. It was moved to morning but eventually was stopped as I just couldn't tolerate it. I don't think it matters what time of day you take it but as many people have nightmares ithat's probably why morning is suggested.

Ramblingross profile image
Ramblingross in reply to Qualipop

I take Bisoprolol at night and I've seen ants on my pillow and grubs in my bed....thank goodness im only dreaming...

Qualipop profile image
Qualipop in reply to Ramblingross

Not surprised. First time t happened I thought my sight had gone.

tigerjuz86 profile image
tigerjuz86 in reply to Qualipop

Hi oh my god that doesn’t sound good that’s eniugh to give you a scare

I have suffered what I think are nightmares but like a weird dream like I feel I’ve woke up but my dreams still going

I might have to try morni see if it stops as they can be unsettling :(

Did you get moved to another medication or are you free x

Qualipop profile image
Qualipop in reply to tigerjuz86

They tried a different medication but I had problems with that too so it was stopped and they decided I didn't need anything at all.

tigerjuz86 profile image
tigerjuz86 in reply to Qualipop

Ahh okay may I ask what you was on them for

I’m on for high blood pressure

Oh okay I guess that’s good than least no side effects for you

Hope you feel okay in yourself without nothing x

Qualipop profile image
Qualipop in reply to tigerjuz86

I was put on the standard list of drugs after a mild heart attack which included bisopralol but I didn't and never have had a problem with my blood pressure so they decided I didn't need them.

tigerjuz86 profile image
tigerjuz86 in reply to Qualipop

Ahh okay I am sorry to hear you went through that :(

Ah okay I understand and I’m glad your blood pressure is good and that you don’t need them no more

Look after yourself and take care :) x

tunybgur profile image
tunybgur

I was also prescribed 1.25mg bisoprolol for tachycardia (after a heart attack). Unfortunately it reduced my already low resting heart rate from 50 to about 44, but it fixed the tachy attacks :-) , my HR used to suddenly jump to 160-180 from 90-100 when just walking quickly.

I take mine in the morning as the levels will be highest during the day, but the blood serum levels should remain relatively stable after a few days.

Cold hands come with beta blockers, but for me it's only really a problem in the winter trying to play golf.

Are you sure your HR is going to 158 when jogging? I wear a HR monitor with a chest band but when I'm jogging the rate is unreliable because of the motion and bouncing around on my chest muscle. It often goes to 180+ but my HR when checked manually is only about 110. At the gym on the X trainer and watt bikes when working just as hard (sweat pouring off me) my rate is 125 max so I tend to ignore my HR monitor when jogging.

I'm 71 and I was also told to keep my HR below 120, but the medics are always conservative.

Good luck

Caitlyn6 profile image
Caitlyn6 in reply to tunybgur

Thank you. I have noticed my Fitbit heart rate varies quite a bit from the gym ones so I might get a chest one. I tend to go by the gym monitor when exercising. But even with gym monitor it could easily hit 160

Rhinet34 profile image
Rhinet34

I’m on the same dose and was told to take them at night

Dickyticker26 profile image
Dickyticker26

Following Chest Pains and 5 hours in the Resuscitation Unit in A & E on 31 July last I was put on Bisoporol 7.5 mg and Apixaban 5mg twice a day

I have had recognisable side-effects of fatigue, dizziness, loss of appetite, tinnitus, dry mouth, nausea and so on but either mild or not long-lasting

Then following an angiogram in mid December revealing "serial severe proximal stenosis" 3 more medications were added-nitrates, statins and clopidogrel

Unfortunately I gradually developed diarrhoea which became constant and lasted for 2 months and which I found totally demoralising

A Joint Cardiology Conference recommended a quadruple bypass in January and I am on a 6/8 week waiting list at St Thomas'

A consultant/surgeon at St George's kindly indicated it would be ok to drop the 3 additional medications on 1 March which had an immediate effect on the diarrhoea and I am back on the original prescription

I have had no more chest pain or the supra ventricular tachycardia I realise now I have had intermittently over some years and which stopped when I cut down on and eventually dropped all caffeine

The cardiologists seem to talk to each other and not to me so much and I am left to pick up what I can from their copy correspondence

The gp will see you right away but seem only anxious to refer you elsewhere and talk vaguely about "plumbing and electrics"

I have been to 5 London hospitals for various tests the latest a vein scan at Guy's last week

I was told by one surgeon that I have the option of doing nothing as I am "asymptomatic" on medication

The image of my heart was projected on the wall of the theatre when I had the angiogram but at the time I wasn't really "there" because of the premed

Otherwise I haven't seen any of the scans but I am learning to put my trust in the experts

I am 80 this month and live with my wife and our 3 now adult children (24,20 and 18) so there is plenty of support at home (I hope)

On balance I will go through with the operation and save my energies for the recuperation process-but I must find out about the medication I will be on after the procedure

Caitlyn6 profile image
Caitlyn6 in reply to Dickyticker26

Good luck with everything. Yes I find the drs advise something but don't necessarily give you all the information you need. Or leave you with more questions.

Katydl profile image
Katydl

I started taking my Bisoprolol 2.5 mg in the morning. After a series of palpitations and a cardiology review. I was told to take them at night.

I tried taking them at night for three consecutive nights and ended up with an excruciating headache, which woke me from sleep. I reverted back to day time and all seems to have settled.

I take Atorvastatin 80 mg at night .

See how you feel when taking them, your body usually lets you know.

Although I'm not qualified to comment on when best to take Bisoprolol (I believe it may depend what other meds are taken at night), but just to comment on the exercise/heart rate thing -

I'd humbly recommend shifting the emphasis from running to cycling, my reasoning is there is far less impact stress on joints. I do run, in fact I don't walk anywhere unless running would get me strange looks... but I don't road run any more.

Cycling however is absolutely superb in the control we have over exertion. I cycle for a few minutes to warm up and then do a 20 second sprint in high gear as hard as I can and then rest/cruise for a minute or two then repeat. When my heart pushes against the Bisoprolol limits then I back off.

I'm actually amazed your Bisoprolol allows you to attain 158!! I can't get past 135 no matter how I push.

Oh, and when I was first in cardio rehab I asked the nurse how far I can run - she said simply "you running days are over"... Never did a phrase depress me as much since my diagnosis. Ha, if she could see me now four years on.

Wishing you the best,

Drew

Caitlyn6 profile image
Caitlyn6 in reply to

Thank you for the advice. I am looking to change from the 'runners high' to the cyclists high, if such a thing exists. Unfortunately the older I get the more things I have to give up that I enjoy.

in reply to Caitlyn6

Hey don't give those things up too easily. it can all come back to an extent. I'm 62 soon (can't believe I'd ever be saying that, grrr), and I'm better than for the last 20 yrs in most respects. Still look like hell but, hey ho.

MichaelJH profile image
MichaelJHHeart Star in reply to

I was told that in the run up to my bypass I had looked like Keith Richards on a bad day! Boy, I must have looked rough!

in reply to MichaelJH

I wish I knew his secret to longevity though 😁

MichaelJH profile image
MichaelJHHeart Star in reply to

In his autobiography (I am a Stones fan) he claims that it is because he could afford to buy the best quality (drugs) and he never took that bit extra. It may be right as they think the death the person I knew was due to cut (contaminated) heroin.

Warning: as they say don't try this at home!

in reply to MichaelJH

Yep lifelong Stones fan here too. 'Exile' still leaves me in rock n roll heaven..

CharlesL profile image
CharlesL

I take it in the morning first thing when I get up. other wise I would forget to take it

altogether

Take care

C

drugs.com/drug_interactions...

I meant to suggest that using a drug interactions checker is a good idea. I take so many different drugs that I find this very useful. It is an American site but is the best one I have found.

Caitlyn6 profile image
Caitlyn6 in reply to

Excellent thank u

Chappychap profile image
Chappychap

I take Bisoprolol in the morning, as per my GP's advice and the instruction leaflet.

I haven't noticed my veins becoming more prominent on Bisoprolol (if that's what you mean by 100 year old hands!).

My experience with pulse rate is the exact opposite of yours. I really struggle to get my pulse much over 115. I'm doing the NHS recommended 150 minutes a week of moderate aerobic exercise (which in my case means a pulse rate around 107), but I could reduce the 150 minutes if I could move up to vigorous aerobic exercise. However, even going like the clappers I'm stuck at 115. I understand that quite a few people have reported a similar effect and believe it's down to a combination of Ramipril and Bisoprolol.

By the way, I had a bypass operation in October last year.

Caitlyn6 profile image
Caitlyn6 in reply to Chappychap

107 is my pulse just moving round the house. Mad. I also take perindopril .

IamMe2 profile image
IamMe2

Interesting reading on bisoprolol. I had a single bypass last April, and have become progressively tireder over the last few months, even thinking about doing stuff seems like hard work! I take 2.5 mgs am with an aspirin and 40mg pravastatin at night. Couldn't find the energy to run now if my pants caught fire! My average resting BP is 51, it has been as low as 39 and did once hit the giddy heights of 62 when I ran out of meds for a week (pharmacy lost my script)

Shame really, as I am known for my normally high energy levels. I am 63 this year so not exactly old.

Sanan76 profile image
Sanan76

Night! I was taking mine in the morning and by lunch time I was so foggy and tired. Moved it to 7pm and it has made a huge difference. Cheers, Steve

Absolutely the root cause in my 'umble view. Sugar>Insulin>Insulin Resistance>Inflammation>Pre-diabetes>Type 2 diabetes>CAD/CVD

The perfect storm...

Everyone learns this eventually I suppose, usually a bit late in the day. It'd be handy if it was taught young.

Lilyrosy profile image
Lilyrosy

Hi there,

So sorry to hear of all the negative experiences with the medical staff.

I am so lucky to live half a mile from The Essex Cardiology Unit and I have had excellent communication from the medical staff right the way through.

After never haven taken medication through my life and a quadruple bypass I was given 1.25 mg Bisoprolol, 10 Lercanidipine but start off with 30mg Lansaoprazaole to protect my stomach.

Told to take them in the morning (all before breakfast) and reluctant at first I have surprisingly felt fine as timing is the same every day. I did refuse a statin as not convinced of the efficacy and the effect they had on my mother and sister who both lost their full mobility but of course that is a very personal thing.

I do wish you well and for all those runners my official BHF stage 4 rehab trainer makes us do intermittent runs in the gym! and his advice his push yourself.

Wadeowen profile image
Wadeowen

I take in the morning, but yes.. randomly have side effects...get terrible bruising, but all ok when checked with the hospital. Related to the other reply, agree...i only take statins at night.. hope you will be ok!

Caitlyn6 profile image
Caitlyn6

Thank you so much to everyone that replied. Very kind and informative. I wish everyone luck in their heart journey ❤️

Cathybm profile image
Cathybm

I have recently swapped from morning to night and the difference is very noticeable to me. I only have 1.25 as I have naturally low BP but every night on my initial falling asleep I would be jolted awake by a feeling I had forgotten to breathe, I also had odd instances of this during the day. Since swapping to night, after consultation with my GP, it has resolved and I actually sleep better. We are all different but it seems the night/day recommendations are open to what suits each of us best. Good luck

starchild8862 profile image
starchild8862

My skin has been very dry since taking heart meds. It seems to dry up everything! I am drinking more water hoping that will help.

Caitlyn6 profile image
Caitlyn6 in reply to starchild8862

Interesting. I have dry skin from immunosuppressant treatment

starchild8862 profile image
starchild8862

I was on losartan for six years and then suddenly came up in hives which left awful scars and are still healing. I suppose everything has some side effects! Good luck with your treatment.

Caitlyn6 profile image
Caitlyn6 in reply to starchild8862

You too. X

allyh1968 profile image
allyh1968

I am on 10mg and take mine at night in case it makes me sleepy etc, my cardiologist advised me that it doesn't really matter when it is taken as long as it is taken x

Honeybun58 profile image
Honeybun58

I was told to take bisoprolol in the morning 10mgs and ramapril at night with statin. Didn't get on with ramapril (cough) so changed to losartan again at night opposite the bisoprolol. Went into AKI so stopped losartan. BP up so now on amlodipine at night. So bisoprolol in morning statin and amlodipine at night.

in reply to Honeybun58

Please what is AKI

Kindly explain

DavidG1971 profile image
DavidG1971

Take mine at night - was making me too drowsy and low on energy when I was on mornings. Has made a big difference to my day. I feel far more normal now.

Stobban profile image
Stobban

The two reasons that I know for the cardiologist to prescribe Bisoprolol at night is simply that first taking that pill makes a person dizzy. Thus, at bedtime you'd be safer lying down. The other is the pumping of the heart at night is disturbed and needs calming as taking the medication in the morning would do little good. Do a little research on Bisoprolol yourself it's great what you will find out.

Scoopdogg profile image
Scoopdogg

I took 2.5 mg every morning - until I saw a private consultant yesterday who recommended I change to nighttime - this is because my blood pressure is quite low - so apparently less of an issue at night

SGH47 profile image
SGH47

Hi I'm 47 years old have LBBB inherited from Grandad, also just been diagnosed with suspected Dilated cardiomyopathy so been asked to take 2.5mg Bisoprolol and 2.5 mg Ramipril but I take these in the morning but cannot function during the day HR goes to 60 bpm, normally before these neds was 85 bpm but would be quite eratic to 130-150 for no reason. Im currently waiting for MRI in 4 weeks to check on dilation etc....and have blood test in 2 weeks as they want to put me on 40mg Astorvastatin I assume I take these at night, anyone have ay ideas please? thanks

QuadroVEINia profile image
QuadroVEINia

I take same dose as yourself at midday and feel relatively comfortable, when I have switched it to any other time I’ve felt lethargic and awful so stick to midday.

Blean7171 profile image
Blean7171

Hi this post is years old now but just wondering if you still have a high HR when you exercise ? I do as well. I just swapped over to Bisoprolol 5mg & saw your post.

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