Recently diagnosed with AF put on apixaban but then endoscopy showed a small ulcer so taken off it. Both these things mean I can no longer take strong painkillers I was taking for chronic back and neck pain which was also helping with the pain in my arthritic knee. I wonder is there any painkiller I can take or take in a different way - like suppository which does not affect either of these. Between all these things and the aggravation caused to colon after the scopes which I had to investigate low blood count I am feeling very low and have lost nearly two stones in the month since my scopes and am getting little or no sleep. I really am at my wits end.