Antibodies Negative

[Annie04]

Hello everyone hope you are all keeping well, in my quest I had been offered the antibody test and although I have been jabbed twice it’s negative. I’m in a flare with Bronchiectasis with a staph infection (it’s been ongoing since February and seems at home now!) so on IVs for the third time. In between many various meds but not successful for very long and it’s dragging back after a short break each time. However, where I felt fairly safe out and about and still SD, masking up etc I feel more paranoid now, having asked the hospital it’s shown that sometimes vaccinations are not so successful in my case in particular.

I’ve been on prednisolone at fairly high levels (asthma) and flares in lungs so I presume it’s not helped this. Has anyone had experience of this?

I’ve been told there are many research areas into this. Apologies for the long post.

[CDPO16]

My husband had an antibody test some months ago and that was negative. I believe that it isn't uncommon.

[peege]

I wonder if means anything that you must be completely run down by now. Please get well soon. P

[sassy59]

Thinking of you and hope you feel better soon. Xxx

[Patk1]

I have read that resistance can show with t cells and cytokines,in some peopleHope u soon feel better x

[Annie04 in reply to Patk1]

Thank you and I appreciate your replies. I will post if I hear of any other news. I’m on the pathway for biologics in between Bronchiectasis so maybe in this area it’s going to shed further information.

Keep safe and well everyone! 🌺

[Patk1 in reply to Annie04]

Id be interested to see how u get on x

[Alberta56]

So sorry you're being plagued by this horrible, persistent bug. Wish I could send it some unfriendly vibes. Hope they get on top of it soon. xxxx

[MoyB]

I am interested to hear how you go on.

I have been jabbed twice but like you, had a flare up in June and, although I have been told the actual infection has gone, my peak flow remains at an all time low. I had a number of weeks on antibiotics and am still tapering off the Prednisolone. I have wondered if all this may have an effect on the jabs and whether or not I am protected.

I will wait with interest to hear what you find out.

Meanwhile, I hope you manage to shake off the infection and that you feel a lot better soon. xx Moy

[Beachballs]

Thanks for raising this , I hadn’t thought about that, and the possible effects of medication. Can understand your anxiety, thanks for sharing. 🌷

[Runrig01]

Was this the NHS antibody test, if so it doesn’t check for antibodies to the vaccine. It only shows if you’ve had the infection symptomatic or asymptomatic. It’s only the ones you buy privately that check for antibodies to the vaccine. Although many on immunosuppressants didn’t develop vaccines, some do.

[Annie04 in reply to Runrig01]

No, it was a GOV test looking for all antibodies, Hospital has said that it can be be a mixture of ailments and treatment. They are also looking at research on this, I was told if I caught Covid there are monoclonal areas of treatment that may help on the NHS. Just unlucky I’d imagine, parting shot is to take everything medically offered.

[Hidden]

It depends on the type of test. If it was the lateral flow antibody test sent out by various research groups in the uk I believe it mainly picks up on antibodies produced by having had covid rather than having had the vaccine.I too was negative for antibodies after two vaccinations, but a friend, who thought she had had covid very early on in the pandemic, was positive.

[Mooka]

Hi Annie you should check out the OCTAVE study. gov.uk/government/news/new-... immune system will be weakened by the steroids hence the booster jab for the immune compromised. However, there’s still research going on in the part that T and B cells play in the fight against Covid.

Have you had your immunoglobulin levels checked? If these are low it could mean your body is not fighting your infection hence your inability to get rid of it. It’s really miserable having constant infections and I hope you can get rid of them soon. 🤗

[Annie04 in reply to Mooka]

I will ask when I go back for my next round of IVs my steroids were around 40mg at the time. I’ve reduced quite a lot since then mainly on 5mg maintenance and increasing on flares. (Aspergillosis) asthma and Bronchiectasis. It’s a pain all of this, consistently fighting pseudomonas prophylaxis (Colomycin) and now this never ending staph. Ironically I feel more ill on staph.

[Foxy79]

Hello Anna I'm foxy79 I'm sorry to hear about your health struggle with broncechtisis hope you get well soon. I have serve copd broncechtisis emphysema respiratory type 2 asthma and odemia I'm on oxygen nebulizer and bipeb machine NIV everyday with lots of tablets know to help yourself I have realized for broncechtisis emphysema respiratory patients best is to stay in a clean area have fresh air as possible like even if can open your window and gets some do it try to sit outside for bit and walk you will see the results and lastly of you can do bit of exercise and loose some weight I know it's very hard with perdiesoline but you have to start from somewhere I was on 70ml never could stop in 10 years I did last few years I was of everything and got my life back then covert-19 came I was home and put on weight and had chest infection etc please have a routine check your diet if you can cut down streiods and bit of physical activity you can be happy Anna try it sorry if I offended you or said anything extra you didn't like take care and good luck with yourself.

[Annie04 in reply to Foxy79]

That’s so kind of you and I totally appreciate your words. Please take care of yourself I can understand it’s hard trying to be well. Strangely its all the small things in life that are the greatest pleasures. Wishing you well.

[Ollie13]

Hi Annie 04 my husband and I have been having monthly antibody blood tests for the ONS my husband comes back positive mine negative. My consultant says it has something to do with my cancer/treatment but like you due to my cancer I have to be 100% careful. I have also heard there are quite a lot of people who may not have antibodies.

[Annie04 in reply to Ollie13]

Oh gosh! Keep safe and well, maybe it’s our immune systems or lack of them, who knows.