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10mg of amitriptyline1st nite trying for pain

Johnj992 profile image
7 Replies

Hi how fast the 10mg of amitriptyline work for nerve pain?

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Johnj992 profile image
Johnj992
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7 Replies
watergazer profile image
watergazer

I would say it depends on your body. I took amitriptyline a few years ago and it took 3 days before the fog cleared and I felt pain free. I took some recently- maybe a lower dose- and took ages. Good luck. Hope your pain subsides soon x

I think the lower dose is a muscle relaxant and that is what aids sleep.

Hope it helps you.

Dixy profile image
Dixy

The pharmacist told me at least 6 weeks. It has to build up.

gillianTS profile image
gillianTS

I was put on amitriptyline for nerve pain it took around 2 to 3 months to start to work fully, it can make you feel awful, not being able to get your head off your pillow in the morning, foggy brain, lethargic. I used to take it earlier in the evening to try and avoid this situation. Unfortunately for me as time went on the drug became less effective and the GP's kept increasing the dose until I decided this was a ridiculous situation and was referred to a neurologist who advised me I should only take amitriptyline for real nerve pain at the time and come off the drug again and back on when required, my GP completely disagreed with the consultant and so Icontinued. Amitriptyline like a lot of drugs mask the real issues and we can and do other things we perhaps should not because of this masking, our bodies become more and more used to the drug and they stop helping in the way they first started to. The go to place for most doctors is to increase the dose, but what happens next, what else is on offer when they have reached the maximum for a drug not intended to go past a certain level for nerve pain. A lot of the time people have tried everything and have nowhere else to go to.

After 9 years of taking amitriptyline I made the bold decision to come off the drug, as advised by the neurologist all that time again. I took 6 months reducing it a teeny bit at a time, withdrawal was horrible. I had a discussion 6 months after fully coming off the drug with another GP about why I still felt the withdrawal symptoms, I was told it would probably take a year or more to completely rid ever cell of this drug.

Good luck.

Spanielblue profile image
Spanielblue in reply to gillianTS

No wonder I feel so tired first thing in the morning and don't want to get up. I was told to take my tablets last thing at night but , in view of what you said, I am going to take them earlier and see if this makes a difference. My Amitriptyline was prescribed for "mood and cough" but not sure if the medication helps much. I did stop taking them a short time ago but kept crying so went back on them again. I hope you have found something else which has helped with your nerve pain.

gillianTS profile image
gillianTS in reply to Spanielblue

Hi, I played around with the time until I got to feel better, it was around 8pm if I recall.

When I came off Amitriptyline I was eventually referred to a rheumatologist who identified from my copious symptoms that I had been suffering all of my life from my mid teens with a rare condition called Behcet's disease and Ehlers Danlos so after trying several drugs they have settled on an immune suppressant called azathioprine which helps some things but nothing like I want it to. My neurologist decided I was getting some kind of migraines, even though I did not feel I had headaches, I laughed when she told me and she said I know you don't believe me... anyway I agreed to try and she prescribed sodium valproate which has been great with my head confusion and although not helped fully with the muscle pain it has a little. I think we just learn to live with our pain and discomfort, this is what I just call normal now.

Take care and I hope you can get the timing of the tablets right.

heavybreathers profile image
heavybreathers

I use 2 times 10mg at night, not for pain but, for tinnitus

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