T-cell Covid immunity 'present in adu... - Lung Conditions C...

Lung Conditions Community Forum

56,314 members66,939 posts

T-cell Covid immunity 'present in adults six months after first infection'.

2greys profile image
12 Replies

Cellular (T-cell) immunity against the virus that causes Covid-19 is likely to be present within most adults six months after primary infection, with levels considerably higher in patients with symptoms, a study suggests.

The data offers another piece of the puzzle that could be key to understanding whether previous Sars-CoV-2 infections – the virus behind Covid-19 – can prevent reinfection, and if so, for how long.

The study, led by the UK coronavirus immunology consortium, evaluated 100 non-hospitalised healthcare workers in March and April after antibody responses were detected in them. It is yet to be peer-reviewed.

It is the first study to offer data on T-cell levels six months after infection in people with mild or asymptomatic disease that is likely to represent the majority of infections, the authors say.

theguardian.com/world/2020/...

Written by
2greys profile image
2greys
To view profiles and participate in discussions please or .
Read more about...
12 Replies
Ian1967 profile image
Ian1967

Hi 2greys, at last some positive news, let’s just hope the T-Cells last as long as the Sars 1 virus, they are still present in patients now after 17 years and have also protected people from getting Covid-19. Dr John Campbell mentions it quite often in his YouTube videos.

Ian.

2greys profile image
2greys in reply toIan1967

This has been my view as well, I have read the same results of studies as Dr John, I have read other studies, as no doubt, he has as well.

I will say this again, in my view of the evidence, B-cells and T-cells are of much greater importance than the initial antibodies are. So what if antibodies declining after time, it is not a great loss, more antibodies will be made 'on demand as needed'.

Very simply put, it is the protein surrounding the virus with SARS-COV-1 is virtually identical to SARS-COV-2. It is this protein that the body uses to produce the respondent B-cells and both helper and killerT-cells. It is also this the same protein that gets dissolved by soap, thus killing the virus.

As you rightly say, the B-cells and T-cells have given immunity to SARS-COV-1 from the time since it first surfaced 17 years ago and still gives active immunity today.

ldwilliams profile image
ldwilliams

This claim is not bing born out in the public though.

I know of several that caught it early on and have no immunity 6 months on when tested. I would suggest all of these reports are taken for what they are, interim results that have not even been peer reviewed, 6% in the larger study is a minimal amount and 10 times less than the so called 'herd immunity'.

Also "this does not yet prove immunity to further infections which will require longer-term surveillance and larger cohorts.”"

This information is Not a saviour

2greys profile image
2greys in reply toldwilliams

You are entitled to your own opinion. There will always be a doubting Thomas.

"I know of several that caught it early on and have no immunity 6 months on when tested".

The only immunity that can be tested for is a serology, antibody test. Not for B-cells and T-cells which is the subject matter. Testing for B-cells and T-cells is something that is not routine at all, it is very complicated, requires a full blood sample and takes a long time to perform, hence very expensive.

As a personal case in point. My partner is a senior carer in a nursing home, That nursing home like most of the other residential and nursing homes were rife with the virus back in April. My partner was infected who consequently passed it on to myself, 4 days later. She has since, tested positive with an antibody test as part of the plasma donation scheme, ergo that proves she had been infected and by inference so was I. She continued to work at the nursing home after a 14 day isolation period (the regulation 10 days from myself presenting the symptoms). Neither of us have suffered re-infection again since April. There were elderly residents who recovered from the virus as well, none of them have suffered re-infection. The nursing home has only been Covid free for 3 weeks since April, that includes all the staff.

Perhaps you can get your grey matter around the facts within this link, which is more than you have provided to back your claim, which in fact has nothing to do with B-cells or T-cells and off topic:

nature.com/articles/s41586-...

I have more links that are a lot more technical to task your grey matter with, if you like. Understand that the newspaper article is written for the general public, who are not medical students, to comprehend.

Davegt profile image
Davegt in reply toldwilliams

I entirely agree with your observations, especially after reading this article. Covid-19 or Sars-Cov-2 does mutate and therefore reinfection with another strain is possible. It is too early to make definitive statements one way or the other just yet.

hospitalhealth.com.au/conte...

2greys profile image
2greys in reply toDavegt

Perhaps you should also read the links I have provided here, which also includes the research paper:

healthunlocked.com/blf/post....

Unfortunately not everyone's immune system is the same and functions correctly, in a small minority it does not.

2greys profile image
2greys in reply to2greys

You still need to read thoroughly:

nature.com/articles/s41586-...

The protein that surrounds the body of the virus does not mutate, that remains a constant. It is the spike protein that mutates.

Davegt profile image
Davegt in reply toDavegt

Too late. Have read.

2greys profile image
2greys in reply toDavegt

But your link:

hospitalhealth.com.au/conte...

Is dealing with antibodies, not B-cells and T-cells. There are just not the same.

Davegt profile image
Davegt in reply to2greys

I know that. Please end this now. I want no further responses. I await definitive expert results.

2greys profile image
2greys in reply toDavegt

Agreed it ends now, as you are NOT on topic.

2greys profile image
2greys

I will just throw this into the mix. If there is no longevity with antibodies then unless B-cells and T-cells give protection over a longer period of time, a vaccine is going to be of no real use at all. The logistics of providing a booster shot every few months after it's effectiveness wears off is not going to happen, it will be like painting the Forth Bridge, get to the end and have to start all over again.

Not what you're looking for?

You may also like...

Singapore scientists uncover SARS-CoV-2-specific T cell immunity.

A Singapore study has uncovered the presence of virus-specific T cell immunity in people who...
2greys profile image

Immunity After COVID-19 Illness May Last at Least 1 Year

Long-term data from northern Italy -- an area hit hard during the early days of the pandemic --...
2greys profile image

Children may transmit coronavirus at the same rate as adults: what we now know about schools and COVID-19

The role children, and consequently schools, play in the COVID-19 pandemic has been hard to work...
2greys profile image

Immunity 91 and 95 days post Covid-19 infection?

Sharon has come home tonight with some bad news. After the nursing home has been Covid-19 free for...
2greys profile image

Silent Spreaders?

In the most comprehensive study of COVID-19 pediatric patients to date, Harvard Medical School...
2greys profile image

Moderation team

See all
AsthmaandLung profile image
AsthmaandLungAdministrator
moderator_AandLUK profile image
moderator_AandLUKAdministrator
Claire_ALUK profile image
Claire_ALUKAdministrator

Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them.

Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked.