In the most comprehensive study of COVID-19 pediatric patients to date, Harvard Medical School researchers based at Massachusetts General Hospital and Mass General Hospital for Children provide data showing that children may play a larger role in the community spread of COVID-19 than previously thought.
The study, published in The Journal of Pediatrics, examined 192 children, adolescents and young adults who came to hospitals with symptoms of or suspected exposure to COVID-19. In this group, 49 individuals tested positive for SARS-CoV-2, the virus that causes COVID-19, and an additional 18 had a late-onset COVID-19-related illness.
The researchers found that infected children carried high levels of the virus, or viral load, in their respiratory secretions, even children with mild or no symptoms. Age did not affect the ability to carry a high viral load, which is associated with increased risk of transmitting the virus to others.
Notably, the team found that infected children in the asymptomatic or early infection phase had significantly higher viral loads than hospitalized adults with severe COVID-19.
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Journal of Pediatrics, the research paper: