Effects of coenzyme Q10 administration on pulmonary function and exercise performance in patients with chronic lung diseases.
Abstract
Serum coenzyme Q10 (CoQ10) levels were measured at rest and during incremental exercise in 21 patients with chronic obstructive pulmonary disease (COPD) and 9 patients with idiopathic pulmonary fibrosis (IPF). The mean serum CoQ10 levels at rest in patients with COPD and IPF were 0.56 +/- 0.20 and 0.45 +/- 0.16 microgram/ml, respectively. In both groups these levels were decreased compared with those of healthy subjects. In the patients with COPD, CoQ10 levels were significantly correlated with body weight, however, there was no correlation between CoQ10 levels and ventilatory function, PaO2, VO2/kg at rest, or maximal VO2. In eight of nine patients whose PaO2 at rest was lower than 75 torr, serum CoQ10 levels were lower than 0.5 microgram/ml.
We studied the effects of the oral administration of CoQ10 at 90 mg/day for 8 weeks on pulmonary function and exercise performance in eight patients with COPD. Serum CoQ10 levels were significantly elevated in association with an improvement in hypoxemia at rest, whereas pulmonary function was unaltered. Oxygen consumption during exercise was not changed, whereas PaO2 was significantly improved, and heart rate was significantly decreased compared with the results obtained at an identical workload at baseline. Furthermore, lactate production was suppressed during the anaerobic exercise stage after CoQ10 administration, and exercise performance tended to increase.
These data suggested that CoQ10 has favorable effects on muscular energy metabolism in patients with chronic lung diseases who have hypoxemia at rest and/or during exercise.
Written by
Dmactds
To view profiles and participate in discussions please or .
As my poor old sainted Ma used to tell me when I asked her to explain something, "Look it up yourself, that way you'll remember it better and it'll mean something to you"; Google is great for research, just watch out for hobgoblins...
Nothing wrong with Google, just as there's nothing wrong with the Encyclopedia Britannica, because that's all "Google" is basically; biggest difference is one has to be a bit more discerning in what one pays attention to; for instance, in health matters, I only land on pages that are home to well established organizations, hospitals, research centers, etc.
That way I cut out the middle man and any misleading or just plain untrue interpretations of whatever the subject of my search is. It can all be very interesting as well. The web is a veritable fount of information..., too much available for it to be ignored.
Earlier today I began wondering what the rate of blood clots and stroke were associated with a particular medicine. I'd read quite a bit on the particular pill but had never seen anything mentioned even though I was/am aware the med has an effect on one's blood. I looked it up by phrasing the question a number of ways and found the answer which was "none" basically. But the point is that no matter how odd one's question, the web has the answer.
Thanks for posting this. I've taken Co-enzyme Q10 myself occasionally as it's supposed to help your energy levels. May now consider buying some more and giving it to my husband too.
It can be bought from health food stores and suppliers. Think it's quite expensive but I'll try anything to improve his condition.
I get mine from Walmart; 90 capsules; not really all that expensive when you consider the benefits.....; personally, I get Qunol Mega with Ubiquinol on the label (that's important as it's the most quickly disseminated through your system).
Between the phlebotomy, CoQ10 and Slo-Niacin, I'm on a "health-roll" that won't stop but I won't know which of the three to attribute any good (or bad) results to; that's not true...., Slo Niacin has already knocked my cholesterol to less than half of what it was, I've had Qunol Ubiquinol before and it's a keeper for sure and the phlebotomy produces a lighter, more buoyant feeling. But this is the first time I've done them all three at once....!!!
Thank you for a very interesting post Dm. I have taken Co-enzyme Q10 for years, at least 10, and though COPD is listed as a degenerative condition mine hasn't worsened since I was first diagnosed in 2002. I started taking it because I was dxd with a heart murmur - that seems to have disappeared too!!! It seems to be a very good supplement and I can vouch for it.
This morning, I went to my first pulmonary therapy session since resuming my CoQ10 last thursday after my phlebotomy the day before: my oxygen count, usually 75 or so without added assistance from a tank was 89, it quickly rose to 94 after adding the tank. My therapist was absolutely bamboozled at the difference. BP was fine as well.
Sometimes, one can fool one's self by playing psycho-drama games convincing one's self something is beneficial when they only wish it was; it's great to have the official backup through actual readings that things have improved. Time will tell how much more.
Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them.
Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked.
Face masks unlikely to cause over-exposure to CO2, even in patients with lung disease.
Comparing Beta-Blocking Effects of Bisoprolol, Carvedilol and Nebivolol
What’s your experience of pulmonary rehabilitation?
