More on CoQ10...

[Dmactds]

..., and here's a link with a bit of copy on tests done on the efficacy of the vitamin:

ncbi.nlm.nih.gov/pubmed/824...

"...We studied the effects of the oral administration of CoQ10 at 90 mg/day for 8 weeks on pulmonary function and exercise performance in eight patients with COPD. Serum CoQ10 levels were significantly elevated in association with an improvement in hypoxemia at rest, whereas pulmonary function was unaltered. Oxygen consumption during exercise was not changed, whereas PaO2 was significantly improved, and heart rate was significantly decreased compared with the results obtained at an identical workload at baseline.

Furthermore, lactate production was suppressed during the anaerobic exercise stage after CoQ10 administration, and exercise performance tended to increase. These data suggested that CoQ10 has favorable effects on muscular energy metabolism in patients with chronic lung diseases who have hypoxemia at rest and/or during exercise..."

(..explanation of PaO2...)

airwayjedi.com/2015/12/09/w...

"...Pa02, put simply, is a measurement of the actual oxygen content in arterial blood. Partial pressure refers to the pressure exerted on the container walls by a specific gas in a mixture of other gases. When dealing with gases dissolved in liquids like oxygen in blood, partial pressure is the pressure that the dissolved gas would have if the blood were allowed to equilibrate with a volume of gas in a container.

In other words, if a gas like oxygen is present in an air space like the lungs and also dissolved in a liquid like blood, and the air space and liquid are in contact with each other, the two partial pressures will equalize...."

[stilltruckin]

Interesting, thanks. I take 300mg/day coenzyme Q10.

[Dmactds in reply to stilltruckin]

Thanks for your interest, StillTruckin.

I went to your personal page and read some of your postings; noticed that on one you mentioned taking Roflumilast and am sending along this info:

medlineplus.gov/druginfo/me...

"... mental health may change in unexpected ways during treatment with roflumilast. You, your family, or your caregiver should call your doctor right away if you experience any of the following new symptoms or a worsening of these symptoms: difficulty falling asleep or staying asleep; depression; thinking about harming or killing yourself, or planning or trying to do so; extreme worry; agitation; or changes in mood. Be sure that your family or caregiver know these symptoms may be serious so they can call the doctor if you are unable to seek treatment on your own.

You should know that roflumilast can cause weight loss. Your weight should be checked regularly by your doctor and you should also check your weight on a regular basis during treatment with roflumilast. If you notice you are losing weight, call your doctor..."

If I'm being 'presumptuous'..., sorry 'bout that...

Duncan

(not R. Crumb)

[stilltruckin in reply to Dmactds]

Thanks, but not had any side-effects. Dig Robert Crumb btw.

[Dmactds in reply to stilltruckin]

I figured anyone with a handle "StillTruckin" would understand the R.Crumb reference; I have several Mr. Natural and other images from the Still Truckin' series/days as mementos since I was living in SF in those days....; glad to meet'cha..., Keep on Truckin'....!!!

Duncan

[teenieleek in reply to stilltruckin]

Good to see you stilltruckin, you've been around this site for years, as I have. Your self-prescribing chimed with me because I used to buy inhalers from a South Pacific island because I wasn't prepared to admit I was ill. After one chest infection too many though, I found myself "in the system".

[casper99]

Thanks for the link Dmactds, for the last year, I have been suffering increasingly weak muscles which I have been blamingvmy other problems for.

As I said earlier, I gave up the coQ10 as I didn't actually feel them doing anything. I also wanted to try the Vitimin A and considered the costs.

After reading this, I realise, that when I gave them up, the summer before last, I had no muscle weakness and was walking much more than the last year and was quite flexible too.

I will definitely be restarting them asap.

[Dmactds in reply to casper99]

It certainly can't hurt and can only help; however, I know nothing about the size of your pocketbook so depending on sources I guess that could put the stinger in...

[teenieleek]

Interesting, thanks. I had high blood pressure some years ago (might still have I suppose, hasn't been tested in years) and was recommended (among other things) co-enzyme Q10. I took it for a couple of years then ran out of pills, kept forgetting to buy new ones and haven't taken it since. It seems to be something that people with a variety of ailments are deficient in so replacing it seems sensible. BUT, there is a limit to how many pills and potions we want to take in a day, I think. I'm taking vitamin D3, a multi vitamin, omega 3 and l-lysine. The latter in bursts, the rest all the time.

[Dmactds in reply to teenieleek]

Including my two inhalers and ventolin which I use only occasionally, I'm up to ten supplements of one kind or another; a couple of blood pressure meds, various vitamins including fish oil and B-12 sublingual.

I've taken vitamins most of the last 30 years or so but it was only about 9 years ago that I began taking any kind of regular medicine; I'm 74 so you might say I got away with it for quite awhile considering many folks start on medications much earlier than that.

I had absolutely NOTHING to do with my excellent good health; it was handed to me on a genetic platter made of silver.

[O2Trees]

Hi Dmactds - I take CoQ10, 100mg a day. It helped take my heart rate down more than 15 beats per minute a while back.

You may well know, but others may not, that there are two forms of CoQ10 - the cheaper and more frequent Ubiquinone and the dearer Ubiquinol. Ubiquinone is poorly absorbed especially in older people, whereas in tests Ubiquinol was found to be 8x more absorbable. Obviously it may depend on your income which you settle for.

Thanks for the post and happy new year

[Dmactds in reply to O2Trees]

O2 Trees,

As with anything, once one REALLY gets into it, it all becomes much more complicated; here's another link that you can follow to befuddle yourself if you'd like, but after the link I've included a blurb from the page that kind'a "nut shells" it, and I believe this is my last entry on this subject for awhile...., at least; I, myself, use Ultra Qunol along with a couple of others:

superfoodly.com/qunol-revie...

"...The takeaway?

If you buy regular ubiquinone, then it is true that Qunol Ultra and Qunol Liquid CoQ10 does have up to 3x better absorption than many other regular forms on the market. Among those, it’s an excellent choice which does seem to have good reviews from customers. This pattern was seen across several leading online retailers we researched.

However if you can afford it, the best CoQ10 to buy in the opinion of many researchers is ubiquinol, since that is in the same reduced form your body naturally uses and studies have suggested it has excellent bioavailability. The good news is you can get it with the Qunol Mega CoQ10 product line, as well as other supplement companies, providing you with plenty of options to choose from.

Whether or not you take ubiquinol versus ubiquinone, regardless of brand, it’s ideal to take it right before a meal/snack that contains at least some fat content, since CoQ10 is a fat soluble substance. That doesn’t mean a burger or fries! A serving of healthy almonds as a snack or some avocado in your salad should suffice (or if you use salad dressing, it probably already is loaded with more than enough fat)...."

[O2Trees in reply to Dmactds]

Yep, that's what i do - take it right before my porridge which has almonds and other nuts chopped onto it and coconut oil stirred in.

[Dmactds in reply to O2Trees]

Found this on Amazon; don't know how it compares to British prices:

amazon.com/gp/offer-listing...

[O2Trees in reply to Dmactds]

Mega-cheap compared with mine! Will investigate further, there's shipping of course, free in the U.S. but wouldn't be to the U.K. Thanks