Dementia Risk & Commen Inhaler - Lung Conditions C...

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Dementia Risk & Commen Inhaler

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Did anyone know risk of dementia from taking popular COPD ASTHMA inhalers use to treat lung disease.

Guess that’s why doctors not really intrested in treating those with lung dieases proactivly AS if lung diease don’t get us drugs used to treat it increas risk of use developing dementia.

One could argue that’s why research is vitally important as this loads of kids take asthma inhalers SO what about there future kids given what we know about errors pass on in our DNA.

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Additionally anticholinergics notably improve exercise tolerance in patients with COPD.

Two commonly used anticholinergics in patients with COPD include ipratropium bromide (Atrovent) and tiotropium bromide (Spiriva).

Shocking part of story IS doctors know anticholinergics cause dementia and have done for years.

I don't know about you but given this snipet of information MAKE me wonder if my cognative inpairment is down to copd lack of oxygen

Or anticholinergics burdon inhalers used to treat my copd lung disease.

You dont want to ask about mysterious copd FALLs and what they know about anticholinergics burdun falls.

EDIT:

We can always find a piece of research with contradicts another piece of research and knowledge is growing all of the time as scientists learn more. Please use the many links provided if you wish to research it further.

Discussion is great but needs to stay polite. Responses are now becoming heated and therefore a decision has been taken to close this post to future replies.

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27 Replies

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7 years ago

Guess it’s all about risk BUT would been nice to be told when given inhalers THEN I might of just asked IS there anything better.

But that smacks at patients choice NOT really in keeping with informed choice MORE just cattle 🐮 going through processes.

Dubba61• in reply to7 years ago

This has been on BBC news today. I dare say, they've known this for some time. Again, we aren't considered priority, in informing. I've been given Spiriva as an extra 3rd inhaler. Very dry mouth n cough with it so, was considering coming off it. This makes the decision easier. Ta. 😊✌️🌻

2greys• in reply toDubba617 years ago

Again there is NO mention of Spiriva or any other inhaler.

• in reply to2greys7 years ago

Here is caption re anticholinergics and copd inhalers

Also i will add even tho am no expert THE lay person can tell if suffering from anticholinergics overload given so called unknown falls incontinance.

But hey what would i know really.

Medicines specifically prescribed for their anticholinergic properties (eg. oxybutynin, benzhexol and benztropine) are well recognised by clinicians.

However, clinicians may be less aware that some medicines prescribed for other purposes also have anticholinergic properties (Table 1).2,6–8 These include the inhaled anticholinergics, ipratropium and tiotropium bromide when prescribed in their usual therapeutic doses. Even medicines with minor anticholinergic properties may contribute to unwanted central and peripheral adverse events.

2greys• in reply to7 years ago

And...where is the link?

• in reply to2greys7 years ago

racgp.org.au/afp/2012/janua...

Ribbon367 years ago

Never heard this before....My Grandmother died of Alzheimers so I already have the family risk....would have been nice to know about this risk as well. Thanks for posting!

• in reply toRibbon367 years ago

The talk about anticholinergics burdon and risk but you wont find research on those with COPD and there burdon count UNLESS we ask.

But you are right WOULD of been nice to have been told SO we could ask if this out better AND if not why not.

But that might smack at cost and accoutability.

Things UK hates

Ribbon367 years ago

I'm in the US and have heard nothing here as well. I take the Atrovent combo in my nebulizer....so it is a higher dose although I have the puffers as well....and used to take the Spireva inhaler too.

• in reply toRibbon367 years ago

Well you are in good country YOU could ask food and drig admin ON twitter about it.

Or share post on your social media.

In UK its old boy network but more that talk about it the MORE that will be done

knitter• in reply toRibbon367 years ago

Hi Ribbon, I take Combivent in my nebuliser too.

Ribbon367 years ago

I don't think our new Pres cares too much about sick people when they are older.....he came into office and raised medical insurance beyond what people could afford.....especially those that are sick and used and needed it.

• in reply toRibbon367 years ago

I know lung dieases asthma dont discriminate AND those who can afford to take action DO if aware.

Then things usally drip down the line .. sorry to hear about health care system or lack OF and insurance companies have lot to anser for AS am sure this will be like CF and how they rip those suffers off when it comes to insurance.

Symes7 years ago

That’s me screwed then. Aside from being on inhalers practically my whole life, I’ve been on anti-depressant medication for the last 5 years.

😔

PMRPete7 years ago

Where does the article mention inhalers for COPD?

"The biggest effect was in drugs used for bladder disorders; such as oxybutynin and tolterodine; antidepressants, including amitriptyline and paroxetine; and Parkinson's disease, including benzatropine and procyclidine.

The study did not find an increased dementia risk from anticholinergics commonly used for stomach cramps, hay fever and travel sickness."

independent.co.uk/news/heal...

• in reply toPMRPete7 years ago

Hi you might need to read more than one study source like a say look up anticholinergics burdon

Study was BMJ in origan not caption from newspaper.

And sure why would they talk about inhalers LIKE they would BUT there it is in black and white anticholinergics in inhalers.

Like i say find me artical or research into anticholinergics burdon and copd.

PMRPete• in reply to7 years ago

"But the new study — which was led by the University of East Anglia (UEA) in the United Kingdom and is now published in The BMJ — discovered that long-term use of only certain types of anticholinergics is linked to higher dementia risk."

medicalnewstoday.com/articl...

ONLY CERTAIN TYPES are linked!

2greys• in reply toPMRPete7 years ago

.....and here is the BMJ link

bmj.com/content/361/bmj.k1315

There is NO mention of Ipratropium bromide nor Tiotropium bromide!

University of East Anglia

uea.ac.uk/about/-/antidepre...

PMRPete• in reply to7 years ago

Anticholinergic drugs and risk of dementia: case-control study, BMJ

bmj.com/content/361/bmj.k13...

As 2greys remarks "There is NO mention of Ipratropium bromide nor Tiotropium bromide!"

BMJ 2018; 361 doi: doi.org/10.1136/bmj.k1315 (Published 25 April 2018)

Ribbon36• in reply toPMRPete7 years ago

I wonder if that includes nortriptyline as being another tricyclic antidepressants or just the specific one that you mentioned.

PMRPete• in reply toRibbon367 years ago

dementiacarestrategies.com/...

Ribbon36• in reply toPMRPete7 years ago

Thanks Pete....It says that nortriptyline has lower AC affects. I took that for panic attacks back in my thirties for many years....but then I see pain killers to which I have had to take for brief periods as well.....like when I had my ankle crushed in a car accident.....I guess there is little possibility to escape things like this completely.....

O2Trees7 years ago

Ive known about this for a while and it's one reason, with dementia in the family, why I haven't wanted to take anticholinergics (Spiriva etc). I'll be sticking with my Symbicort. Good to hear that Ceterizine used for hay fever etc isn't a risk.

• in reply toO2Trees7 years ago

Hi O2Trees where did you hear about it.

O2Trees• in reply to7 years ago

To be honest I can't remember Jeff, which probably means it was a while ago and it's kind of sunk into the far reaches of my (so-called!) brain.

2greys• in reply toO2Trees7 years ago

Yes, I can confirm that this story has been around for quite a while. Like Jan 2015 at the least.

news.medicine.iu.edu/releas...

knitter7 years ago

Atrovent is classed as an anticholinergic medication I think. I have taken that for years.