Dated August 2016, which I suppose is fairly recent.
Here are a few choice excerpts:
4-AP has been investigated extensively as the leading compound for axonal
functional restoration efforts following myelin damage in both SCI and MS
4-aminopyrdine-3-methanol (4-AP-3-MeOH), showed similar efficacy, a 10-fold increased potency and overall less side effects in restoring electrical conduction
in injured axons
In addition, both 4-AP and 4-AP-3-MeOH were tested side by side in the same study for the first time. This study confirmed that 4-AP-3-MeOH works to restore conduction in axons with acrolein-mediated myelin damage and also displayed greater efficacy and wider therapeutic range than 4-AP
A lovely scientific report, the only disease it mentions is MS, but it's all the same to me. 4-AP and 4-AP-3-MeOH benefit a whole range of demyelinating diseases.
They certainly work for me.