Spirononolactone and Dapaglifloxin.

[AFCyclist]

In my copy of a letter from my EP to my GP he has suggested that I should start taking the above 2 medications. This has not been discussed with me despite a 6 monthly phone call with my EP a couple of weeks ago! I will be talking to my GP about this proposal but wondered if anyone else had experience of these medications? They appear to be to help my cardiomyopathy and LBBB. I have Googled them. I aalready take Losartan, Sotalol, Warfarin and Atvorastatin and would prefer to minimise medication where ever possible. I am 74 and been suffering increased AF attacks and I am on the list for a follow-up ablation. Any comments about experiences with Spirononolactone and Dapaglifloxin would be welcome.

[Crystalbowl]

I have been taking both for some time, the Spironolactone longer than Dapagliflozin. I don’t take any of the others you mention though although I do take others, namely Entresto, Nebivolol, Digoxin, Fuorsemide plus a couple of others for different conditions. Despite fighting to stay off drugs for a long time, I do seem to have adapted to them quite well with few, if any, issues including the two you ask about. I am 76 with permanent AF, moderate heart failure with CRT pacemaker implanted. At last echo, my ef had gone from about 35% to 54% so something is working.

[2learn in reply to Crystalbowl]

hi, I was given Spironolactone, but within a month I started having common side effect of very sore nipples and breast enlargement, told my GP and he took me off it straightaway. I'm male, aged 73.

[AFCyclist in reply to 2learn]

Hmmmm... something to watch out for if I decide to go ahead!

[AFCyclist in reply to Crystalbowl]

Thank you that is helpful. I also have a pacemaker designed to kick-in below 50bpm. It is only 2 lead as they could not get the third lead to attach so I do not get any synronisation of my LBBB. Good to hear that your medication and pacemaker is giving you some improvement.

[Silvasava]

FWIW I take half a tab of spironolactone, down from a whole tablet and been on it for about 2 years and was put on Dapagliflozin last year. I've had no issues with either. I have DCM and Afib. I'm also on Entresto, Atorvastatin , Digoxin, Edoxaban. I also been on Thyroxine for the last 30years. I'm 76.

[AFCyclist in reply to Silvasava]

That is good to hear. Thank you.