Nebivolol dose : Hi I have been on 2,5mg of... - AF Association

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Nebivolol dose

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Hi I have been on 2,5mg of nebivolol for 3 months and my life has literally been transformed. I have atrial fib and flutter and literally nothing worked and bisoprolol drained me and caused extreme chest pain. When I picked up my last prescription it was for 5mg and told me to break in half and now after a week I am back to square one! It was ok for the first 2 days but then I began having short episodes again and having to take the other half Any advice Is this a cost issue?

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Well there appears to be a huge difference in cost. So I understand why I have to split the tablet in two.

bnf.nice.org.uk/medicinal-f...

I have found a dose equivalence between Nebivolol and Bisoprolol in terms of benefit, but Nebivolol has fewer side effects for me.

I have permanent AF/AFL. At my next appointment I will ask about adding a small dose of Digoxin and reducing the dose of Nebivolol. I know that NICE don’t recommend Digoxin for active patients. Not sure about that. I had relatives who were on Digoxin for AF and were very active in to their late eighties.

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cassie46 in reply to Hidden

I was on Digoxin for about 9 months but had to come off it because it affected my memory - names of people were the worst thing, I could remember there first or surname but not full names and sometimes nothing. When I came off it all was normal within a few weeks, I was prescribed Diltiaziam instead was also taking Bisoprolol at that time but I have changed to Nebivolol at the beginning of this year. I would never take Digoxin again, I think Jean had a load of problems with it as well.

Cassie

If your having problems. Again I suggest you go back to your doctor and let them know Maybe it's been a mistake this reduction We all know it can happen unfortunately

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Hidden in reply to Vonnieruth

Its not a reduction its the fact that the original prescription was for singe 2.5 tablets and now I am breaking 5's in 2 and they don;t seem to be working Could it be the brand?

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Vonnieruth in reply to Hidden

Could be brand or dosage if not exactly half

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Hidden in reply to Vonnieruth

Thanks that is what I am thinking as I had an old one in my purse as an emergeency which I took and it kept my heart steady all day whereas this seems to wear off about 4-5pm

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Vonnieruth in reply to Hidden

Check if the new ones are film coated Someone on here mentioned they had noticed a difference if they were

Hi Teddy :-) I take 2.5 mg Nebivolol and was told by my Doctors practice I would have to change to 5mg and cut them in half because 2.5 were too expensive but I said I didn't think I could get an accurate dose so they left me alone.

I would go back to your GP and say you are having a problem cutting them in half and getting an accurate dose.

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Hidden in reply to doodle68

Thank you I think I will it has made such a huge difference the last few months being able to breath again etc and I am so sad to be back where I was

I don't know the size and shape of Nebivolol tablets, but have you tried using a pill splitter if you have to divide them? They are not expensive. I used to use one to split bisoprolol tablets (which I no longer take) and the splitter cut through those cleanly.

I too am on Nebivolol but on 5mg. This may be a completely daft thought but when a drug is mixed with it's filler how can they be sure it is mixed evenly, the 5mg of drug is there but also a lot of filler!!!!!!!!!! If you compare a 5mg tablet of Biso it is tiny compared to a 5mg tablet of Nebivolol which is about 5 times the size so I reckon there is a lot of filler in it. Just a theory.

Cassie

I have moved from 10mg bisoprolol to 5mg Nebivolol and just last week had that raised to 7.5 to try to slow my pulse a little. The point is I got the tiny 2.5 pills to raise my dose. Ask again at the pharmacy.

Wow just read the tariff prices. That is astonishing. 2.5 is a tiny wee pill but why so expensive?

Okay this is worrying as I had the opposite problem. I'm on 7.5 mg a day so am prescribed the 5mg tablets and take 5mg in the morning and 2.5mg in the evening. But a few months back the 5mg were on backorder so the chemist gave me 200 2.5mg tablets.

And guess what - 10 days later I was in AF. I ordered a repeat and got some 5mg tablets and the AF went away.

So there's obviously something different between the tablets. It isn't the cutting in half as there is a break mark on the tablet and they only put those if they guarantee a reasonably even spread of the active ingredient. But I wonder if there are different formulations of the filler that disagree with us, or stop the active ingredient being digested.

I would certainly ask your GP for some 2.5mg ones again to test if the problem goes away. I know years ago I could only use one brand of asthma inhaler, and nowadays only one type of GTN spray works for me.

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