Statins anti inflammatory effect on ... - Atrial Fibrillati...

Atrial Fibrillation Support

32,291 members38,566 posts

Statins anti inflammatory effect on arthritis?

8 Replies

My docs say no, I say “ what say you?”. I reluctantly agreed to take Lipitor 80 mg daily( Atorvastatin) as my cholesterol continues to rise in spite of my exercise, healthier eating and 45 lb wt loss😢. I was skeptical as all I’ve heard were negatives re side effects. After 3 mo, no side effects yet BUT my arthritic painful knee that has bothered me for 10+ yr is now painfree on most days. The pain went away suddenly after about 3 weeks on lipitor. All my docs say no connection. After googling Lipitor and reading about anti inflammatory effects of statins, I think I disagree. Anyone else here have any similar experience with statin drugs? It feels so great to be able to walk a mile or two pain free now💜

Read more about...
8 Replies
jeanjeannie50 profile image
jeanjeannie50

That's interesting to hear Hoski. How lovely it must be to be without your knee pain.

It would be great to have a good side effect from a drug for a change. Will watch your answers with interest.

Jean

BobD profile image
BobDVolunteer

Interesting that. I stopped them about a year ago due to muscle paian in my legs. My knees didnt get any worse. Shows how we are all different.

in reply toBobD

Im hoping once I get my bmi down from now 30 to 25 and I’m as healthy as I can be... to work my way off of as many drugs as possible

sleeksheep profile image
sleeksheep in reply toBobD

I reduced my atorvastatin dosage to 5mg a day because of calf pain and surprisingly my cholesterol still dropped. No more leg pain but still a bit concerned with the effect it can have with diabetes 2 .

As with the latest information with perindopril ( ACE inhibitors ) theres a lot still to be researched with some of these high usage prescriptions.

bmj.com/content/363/bmj.k4209

I would have thought that as you have lost 45lb, that that would take a lot of pressure off the knee and could account for the improvement. Certainly, weight loss is recommended for arthritis of the knee. It’s obviously good news for you whatever the explanation is!

in reply to

That’s what my docs say too, and I agree. It was just a sudden absence of pain, like one day I realized my knee doesn’t hurt. What ever the reason, I’m totally thankful for it and hope it lasts. Walking is one of my joys, haven’t been able to do it much. Hoping the a fib follows suit. It has been in hiding for about 6 mo now

Well it seems logical because statins work in coronary artery disease because of their anti-inflammatory effect, nothing to do with cholesterol according to my cardiologist.

nhs.uk/news/medication/stat...

I bet your 45lbs weight loss is responsible. Well done !

Not what you're looking for?

You may also like...

Lipitor vs other statins

My cardiologist changed me from lovastatin to Lipitor after heart attack. Lipitor has a lot more...
Jlaine profile image

Anti inflammatory action of statins

Hi I saw my stroke consultant yesterday and told him I'm struggling with atorvastatin. I'm supposed...
Gilldy profile image

Anti-inflammatory with Asthma and on warfarin

I could do with some suggestions please. At any point in the next three months I will be having my...

Anti coagulation worries

After being on bispoprolol for 18 months after pacemaker fitted, hospital forgot all about me and I...
wpw62 profile image

Medscape article...placebo effect

I know I did not have placebo effect after my first ablation. Now as I'm facing my second and got...
Eliza2 profile image

Moderation team

See all
Kelley-Admin profile image
Kelley-AdminAdministrator
Emily-Admin profile image
Emily-AdminAdministrator
jess-admin profile image
jess-adminAdministrator

Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them.

Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked.