I have been on Flecainide, Ibersartan and Warfarin for my PAF for more years than I care to remember and last year diagnosed with Wet macular degeneration, So now have injections and 2 different eyedrops
My question is does anyone else have side effects from the eyedrops namely Brinzolomide and Zalatan? I was taken off Timolol as it is has betablocker in it.
This was on the advice of the Dr in A & E after a cardioversion.
Your thoughts would be appreciated Jo.
It’s probably me Jo, I’m very old and very past it, but your title is confusing me.....do you mean your INR is changing since using the eye drops as I cannot see the connection with “side effects” from the eye drops....don’t be afraid of making me look stupid......Beancounter (one of the volunteers) does it all the time.....😉😂
No nothing to do with Warfarin that was just information.I was asking if it affected the the Atrial Fibrillation in any way, for example tiredness, breathlessness. I am sure I am not expressing myself very well but all these eyedrops medications seem to have bad side effects, ,
Kind regards Jo
That's fine Jo, the difficulty is that I suspect the number of people on the forum who use these eyedrops and therefore have the necessary experience to offer advice are relatively small, but hopefully I will be proved wrong. I have to point out that I'm not medically trained, but I googled both types of eye drops and almost all the side effects listed related to the eyes only although one mentioned tiredness as a rare side effect. As we know, all medications have a list of side effects that seemed designed to scare the pants off you, but if I were you, I would speak firstly to your pharmacist and possibly an optician. One of the forum members maybe able to help more and I will email her and I'm sure she will help if she can...….sorry I'm unable to be more helpful...
Thank you
Hi TenorJK, I was diagnosed with Glaucoma many years ago and had all the usual drops prescribed, too many to list, but I had a problem with them setting off my PAF and this to me wasnt an option as I had a cryoablation and I didnt want to upset my heart again.
I had a couple of eye ops and have check ups, always asked what drops I use now. I value the health of my heart and eyes but its a balancing act.
All the best
Jackie
Thank you for your reply I shall mention it to the Cardiologist at the next appt, but was interested to see if anyone else had any experience.
I have been on eye drops to prevent glaucoma for several years. I also sometimes have mild asthma, and for months at a time cannot seem to shake off excessive lung mucus, which is often infected. The battle has gone backwards and forwards over the years. But I have not stopped taking my eye drops.
Most doctors I talk to -- eye and heart -- will think that eye drops have a minimal effect on the body, in my case, lungs and heart. But, just to be safe, they have avoided giving me the cheaper betablocker only eye drops.
Brinzolamide
The recommended frequency for topical application is two times per day. Following ocular instillation, the suspension is systemically absorbed to some degree; however the plasma concentrations are low and generally below the limits of detection (less than 10 ng/mL) due to extensive binding by tissues and erythrocytes.
en.wikipedia.org/wiki/Brinz...
When nasolacrimal occlusion is used or the eyelids are closed for 2 minutes, systemic absorption is reduced. This may result in a decrease in systemic side effects and an increase in local activity. medicines.org.uk/emc/produc...
My concern is that the eye drops might contribute to triggering AF. I think this risk is tiny. If you do not get on with betablockers, there are alternatives as you note though the amount in the combination products such as Duotrav is tiny.
There do seem to be options out there, so do talk about them. Another point, some of them require keeping in the fridge. That is a real nuisance especially when travelling. When I mentioned that, the eye doctor said I should have spoken before, and put me on a room temperature alternative (Duotrav = Travoprost + a little Timolol).
My husband has glaucoma and has regular injections. The specialist warned him that blood thinners are inadvisable before the injection in case the needle hits a vein in the eye. He suggested consulting the GP and possibly not using them before (as before an operation or a tooth extraction). (My dentist always insists on a blood test the day before.) I know this is not quite what you are asking but I thought it'd be useful to know.
Thank you for your reply.I have had 8 injection and never told to stop warfarin. it was the same at the dentist although he did enquire the INR number and if within range no problem.
It seems different Drs different advice. I am in the UK.
Regards Jo
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