Had one in the last eleven years of warfarin and that was at night. Woke up with some clots in my mouth but no current bleeding. Get your INR checked asap just in case.
Hi Lainie,
I was diagnosed with paroxysmal AF in Jan 2010. Some months later after returning to work driving buses I began nose bleeds, full flow but lasting only a short period of time. Sometimes these would start when I was off duty at home other times when I was on shift and driving. My medication for AF then .... and still is ... Warfarin 5.5 mg daily and Bisoprolol 5 mg daily. I went to my GP and did some table thumping. She looked up in her book of 'Magic potions and brews' and asked when I was taking it - I said - in the morning, as prescribed originally. She said - take it at night when you take your warfarin and other night time medication. I did that and have NEVER had a nose bleed since. Warfarin might be the problem, but, don't be too hasty blaming poor old warfarin (which seems to be always blamed for everything) rather consider your total medication package and the timing of it. Her logic, rightly or wrongly was that the Bisoprolol then started to work at night while the body was resting and not undergoing the pressures of Bisoprolol getting to work during the day when the body as working full on .... so to speak. I dunno really, BUT - that's what happened to me.
I would also add that in those early months the Bisoprolol really gave me a hard time but I carried on with it and now Bisoprolol and Warfarin are my very bestest mates !!
I was told by the lead Anticoagulation nurse at the hospital that does INRs around here that with warfarin there is no magic about taking it circa 6.00pm to 8.00pm except that if they have to alter the dose (especially in the first month or two) the change dose comes into effect 14 or 16 hours earlier. However once people are very stable makes little difference because it has long half life.
Re beta blockers (and some other drugs taken once a day) I was told that the logic is that by taking them first thing in the morning their effect is stronger during the day when we are doing things (so keeps down heart rate for beta blockers) and the effect is less at night when HR is lower. If someone has a low heart rate and takes it at night then HR could become dangerously low and similarly go too high during the day.
Thanks. I rang the pharmacy and apparently it doesn't matter when you take atenolol, but sometimes they start you on it at night in case you feel dizzy. I've taken it for 14 years and used to take 25mgs twice a day but am now taking only 25mgs.
Yes. Sounds familiar. I was on a NOAC for a short time and they stopped. Sometimes very heavy. Once I had to be hospitalised. Every morning I wake up with clots in the one nostril. Definitely the warfarin fir me.
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