I've posted extensively here about flecainide's ability to suppress the brain's immune system and how that probably led to my autoimmune disorder following my successful ablation exactly one year ago. Well, I might owe the drug an apology.
It seems that the culprit might be mast cells, rather than hopped-up microglia. There's a poorly-understood dynamic called mast cell activation disorder (not to be confused with mastocytosis) that can produce all kinds of really nasty effects. I've been taking a mast cell stabilizer called Quercetin for the past two weeks and I'm seeing a pattern where previously the symptoms had been quite random. They're also milder and of shorter duration, with a few exceptions.
I believe my previous posts indicated that flecainide's implication in my disorder was a theory and that I wasn't certain. I hope that's enough to prevent a lawsuit for defamation of character. This is a real concern. Here in the US, corporations have constitutional rights. It would be no surprise to learn that their products also have rights, just as someone born here is automatically a citizen.
OK, tongue out of cheek.
The jury is still out on whether mast cells are the real bad guys, but at this point I have to retract my previous excoriation of a popular and effective medication.