Ogorvyx + Xtandi only TX for Gleason 9 oligometastatic

[7OaksTom]

I have a friend who was diagnosed with Gleason 9 oligometastatic PC 9 months ago. His only treatment has been Ogorvyx and Xtandi. His PSA is undetectable.

How did he escape RP or RT?

[Tall_Allen]

Your question should have been "How did he escape triplet therapy?"

He can have debulking of the prostate at any time.

[7OaksTom in reply to Tall_Allen]

So why are we being debulked if the anti androgen meds kill the tumor and mets?

[Tall_Allen in reply to 7OaksTom]

Because anti-androgen meds don't kill all the cancer cells. That's why triplet therapy increases survival and why debulking increases survival if one has 3 or fewer metastases.

[Eye2eye in reply to Tall_Allen]

HelloTall_AllenHusband G10(9/12+ve)

T4 N0 M1(3mets on spine 1L pelvic segment.)

My husband's ref from urology to Oncology was 5 wks too late for triplate therapy, permitted under nhs. He has been on Degarelix since 14 Oct 24 psa dropped from 4,432 to 7 now 6.33. To be checked gain in 1wk Deg is to be swapped to Prostap today He started Docetaxyl 3wks ago. (Tolerated v well so far) Am I correct in believing this is doublet therapy. Please explain about "debulking" prostate . Is this what we hope the chemotherapy is going to do. Oncologist hhas said will have RT 6-8 wks after Docetaxyl has finished . I would be v grateful for your thoughts.

Thank you for your information & comments on this & your others.

Sue

[Tall_Allen in reply to Eye2eye]

You are correct. Doublet means two therapies at the same time - in his case docetaxel +Prostap.

This explains about debulking radiation to the prostate that seems ideal for him:

prostatecancer.news/2018/09...

[Eye2eye in reply to Tall_Allen]

Thank you so much.

[j-o-h-n in reply to Eye2eye]

Greetings Eye2Eye,

Would you please be kind enough to update your Dear Husbands bio. Thank you!!!

Good Luck, Good Health and Good Humor.

j-o-h-n