Why Cabazitaxel instead of 2nd Docetaxel?

[davebliz]

For people that Docetaxel worked, why do they typically switch you to Cabazitaxel for the 2nd time of chemo instead of repeating the Docetaxel? Thanks.

[Tall_Allen]

Because some of the cancer may be docetaxel-resistant. But docetaxel might continue to work if it worked well before.

[MarkBC]

Good question. I responded really well to docetaxel when diagnosed six years ago. My oncologist suggested that we might try it again once my current abiraterone / ADT regimen starts to fail.

[timotur]

Some prefer Cabazitaxel due to its reported lower side effects, but in many cases, it's not covered by insurance as first option.

[dhccpa]

When you say that docetaxel "worked," can be you be more specific about what you mean and how that was determined, particularly since you now find additional chemo necessary?

Thanks for the clarification.

[davebliz in reply to dhccpa]

Like most of my different treatments, it held the tumors at bay for several months. But unfortunately about 2 months after I stopped Docetaxel, my PSA started rising and tumors increased.