Metastatic pathway discovered???

[Aardvark4]

Well, this may be a long shot but a friend of mine listened to a radio broadcast on BBC radio 4? about a pathologists discovery of a previously unidentified circulatory system!

My understanding of what was said

The abstract version - When tissue is prepared for slicing in a microtome the end result is a sample with microscopic 'cracks' when viewed under a microscope. These were examined back in the day of lower power instruments and assigned to being caused by drying out during the embedding process.

Seeing these 'cracks' in multiple tissue he decided to investigate their eitieology by taking a sample of fresh tissue straight to microscopically examining it. What he observed looked to him not cracks but microvessels. He contacted a colleauge with higher resolution equipment and together confirmed a new vessel network.

Not only that but studying a tissue/tumour sample they observed cancer cells filing one by one along the vessels! They examined multiple body tissues and found these vessels throughout, other than in the uterus. A preliminary estimate pointed to a total collagen-like liquid volume greater than the blood system!

As I have only come by this second hand I tried and failed to track down the programme, so any help from anyone out there with knowledge of this would be appreciated.

If this pans out I would like to think medico-scientists around the world are frantically repeating the findings. Or maybe bigpharma is waiting to see if anything is patentable.

Thanks in advance

[Nwdx]

Is this the referenced article or subject?

"Glowing dye helps see hidden prostate cancer cells

9 June 2024

By Aurelia Foster,

Health reporter, BBC News"

bbc.com/news/articles/ck77k...

A related article I believe (however the link to Springer from the above article did not go to the specific study):

Enhancing surgical outcomes: accurate identification and removal of prostate cancer with B7-H3-targeted NIR-II molecular imaging

link.springer.com/article/1...

[Aardvark4 in reply to Nwdx]

Thanks for your efforts but I don't think so. I'll have to grill him for more details. He's in today for an angiogram/stent++, so I'll give a breather before nagging him. I do hope it was'nt April the first when he heard it!

[j-o-h-n in reply to Aardvark4]

Did you try calling "BBC radio 4?". BTW would you please update your bio (age? location? meds? treatment center(s)? doctor(s)? PSA? Gleason? and etc.) all data is voluntary but it helps you and helps us too. Thank you!

P. s. you are the first in line,,,

Good Luck, Good Health and Good Humor.

j-o-h-n