This is Cebubob, Stage 4 Pca.
I found this research paper: ncbi.nlm.nih.gov/pmc/articl...
This off label supplement sounds promising in this paper. Does anyone use this supplement and if so, any measurable results? If not, why not? Thanks in advance.
I've never taken as a supplement, but I suspect I get it regularly on the plant based diet. I guess dosage is the key, though.
from H.U. 6 years ago..
A Novel Flavonoid Composition Targets Androgen Receptor Signaling and Inhibits Prostate Cancer Growth in Preclinical Models.
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pjoshea13•
6 years ago•8 Replies
New study below.
The novel composition has 3 familiar components: luteolin, quercetin, and kaempferol.
"The high prevalence and long latency period of prostate cancer (PCa) provide a unique opportunity to control disease progression with dietary and nutraceutical approaches. We developed ProFine, a standardized composition of luteolin, quercetin, and kaempferol, and investigated its potential as a nutraceutical for PCa in preclinical models. The three ingredients of ProFine demonstrated synergistic in vitro cytotoxicity and effectively induced apoptosis in PCa cells. ProFine markedly affected the transcriptome of PCa cells, suppressed the expression of androgen receptor, and inhibited androgen-regulated genes. Oral administration of ProFine did not exhibit obvious toxicities in mice, and the three ingredients retained their individual pharmacokinetic and bioavailability profiles. Importantly, ProFine significantly retarded the growth of PCa xenografts in athymic nude mice and extended the survival of animals. This study provides preclinical evidence supporting the promise of ProFine as a safe, efficacious, and affordable intervention to control PCa progression and improve clinical outcomes."
-Patrick
ncbi.nlm.nih.gov/pubmed/299...
Neoplasia. 2018 Jul 4;20(8):789-799. doi: 10.1016/j.neo.2018.06.003. [Epub ahead of print]
A Novel Flavonoid Composition Targets Androgen Receptor Signaling and Inhibits Prostate Cancer Growth in Preclinical Models.
Mamouni K1, Zhang S2, Li X1, Chen Y1, Yang Y1, Kim J3, Bartlett MG3, Coleman IM4, Nelson PS4, Kucuk O5, Wu D6.
Author information
1
Molecular Oncology and Biomarkers Program, Georgia Cancer Center; Department of Biochemistry and Molecular Biology, Medical College of Georgia, Augusta University, Augusta, GA, USA.
2
Department of Urology and Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA, USA.
3
Department of Pharmaceutical and Biomedical Sciences, College of Pharmacy, University of Georgia, Athens, GA, USA.
4
Division of Human Biology, Fred Hutchinson Cancer Research Center, University of Washington, Seattle, WA, USA.
5
Department of Urology and Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA, USA; Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA, USA.
6
Molecular Oncology and Biomarkers Program, Georgia Cancer Center; Department of Biochemistry and Molecular Biology, Medical College of Georgia, Augusta University, Augusta, GA, USA; Department of Urology and Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA, USA; MetCure Therapeutics LLC, Atlanta, GA, USA. Electronic address: dwu@augusta.edu.
PMID: 29981500 DOI: 10.1016/j.neo.2018.06.003
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bladder conditionsquercetin
Good Luck, Good Health and Good Humor.
j-o-h-n
seems like: eat Kale!
and Broccoli, thanks. Chop the kale very small and add to soups, otherwise, no.
Similar, FYI: (Black pepper and Cardamom)
pubmed.ncbi.nlm.nih.gov/202...
Remarkably, it is evident that black pepper and cardamom extracts significantly enhance the cytotoxic activity of natural killer cells, indicating their potential anti-cancer effects.
4-MU (4-Methylumbelliferone)
The FDA List of Fake Cancer Cures
Some Difficulties Translating Scientific Studies into News We Can Use
Suppliments that help with chemo?
Leg cramps in the morning 
