Bilateral frontal calvarial metastases

[kklott01]

Has anyone in the forum experienced bilateral frontal calvarial metastases associated with their PCa? I recently had a brain MRI where this metastases was identified.

The assessing physicians impression was that there is no worrisome parenchymal or leptomeningeal enhancement and did not recommend any actionable items or recommendations at this time.

I have been feeling low pain headaches and am considering having radiation therapy performed to this area if the headaches or symptoms become worse.

Has anyone in the forum experienced a similar situation of metastases and undergone radiation therapy in this area? I'm concerned about potential risks of the radiation but haven't yet had a discussion with the head of MD Andersons radiation therapy department. I am also a new participant in a CDK4 inhibitor trial trial through MD Anderson, but don't know how long I can afford to wait before utilizing radiation therapy to extend my life.

Appropriate feedback appreciated.

[GP24]

You could ask the head of MD Andersons radiation therapy department if you could be treated with proton beam radiation. This kind of radiation could be done without affecting the brain.

[kklott01 in reply to GP24]

I appreciate the feedback and suggestion, I will ask about that specific therapy option. Thanks!

[Tall_Allen]

Headache is a known side effect of CDK inhibitors (20% incidence).

[MaxWife]

had a left parietal calvarial lesion on PSMA scan. Doc said not to worry that it does not spread to brain. 6 months later had 4cm right tempoparietal brain mass discovered after new onset seizure. I would get brain MRI and consult Radiation Oncology. They can treat these lesions and monitor for other head/brain metastases as they show up.

[j-o-h-n]

From Ai.

Bilateral frontal calvarias metastases refers to the presence of metastatic cancerous lesions on both sides of the frontal bone of the skull. The term "bilateral" indicates that the metastases are present on both sides, while "frontal calvarial" specifies the location on the frontal bone of the skull.

Metastases occur when cancer cells spread from their original (primary) site to other parts of the body through the bloodstream or lymphatic system. In the case of bilateral frontal calvarial metastases, cancer cells originating from a primary tumor elsewhere in the body have traveled to and formed secondary tumors in the frontal bones of the skull.

The management and treatment of bilateral frontal calvarial metastases typically involve a multidisciplinary approach, including surgery, radiation therapy, chemotherapy, and other targeted therapies, depending on the primary cancer type, the extent of metastasis, and the overall health of the individual.

Good Luck, Good Health and Good Humor.

j-o-h-n

[kklott01 in reply to j-o-h-n]

J-o-h-n thank you the feedback, very much appreciated!