PET Scan Results 030424: New PSMA avid... - Advanced Prostate...

Advanced Prostate Cancer

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PET Scan Results 030424

alperk profile image
6 Replies

New PSMA avid sclerotic lesions in the left inferior pubic ramus, and bilateral symphysis pubis.

Additional new small foci in the left acetabulum and supra-acetabular region. Index focus in the left symphysis pubis with a maximum SUV 20.4.

RO will radiate but suggests change from Zytiga to Xtandi. I am playing whack-a-mole but want to stay on Zytiga as long as possible because Xtandi will also eventually fail and the next step is not so good. What do you think, my friends ?

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alperk profile image
alperk
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GP24 profile image
GP24

Xtandi will work for a few months only after Zytiga.

Tall_Allen profile image
Tall_Allen

You might get more mileage out of Zytiga by switching from prednisone to dexamethasone, and by killing off those resistant tumors with SBRT.

vintage42 profile image
vintage42

How long have you been on Zytiga? I am on Orgovyx, just started Zytiga, and wonder how long it might work.

daysbetween profile image
daysbetween in reply to vintage42

Check this link out....there are patients in this thread that have been on Zytiga for up to 10 years and going strong -> healingwell.com/community/d...

alperk profile image
alperk

29 years after cryosurgery to remove prostate, PSA jumped, had scans and was diagnosed in August 2021. Treatment was Eligard, Zytiga and Prednisone. Zytiga appears to be failing but I am riding it as long as possible with SBRT. Also recently switched to Orgovyx.

Jrb12 profile image
Jrb12

For me, I had no side effects. Xtandi did what it was supposed to do and kept things at bay for close to 30 months. Looking back I think I was prescribed it prematurely. I have since had chemo, Keytruda and Pluvicto.

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