Lupron Shot - Numbness in Quads Muscles - Advanced Prostate...

Advanced Prostate Cancer

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Lupron Shot - Numbness in Quads Muscles

FightCancer101 profile image
26 Replies

I got my 1st Lupron shot into right hip muscle 4 weeks ago. It was painful! But pain went away in 5 min. 3 weeks later I started experiencing pain in my quads and some numbness.

I was told that next time, it's preferred to do it in the left hip. I'm afraid, I might have the same problems with my left quads after the next shot.

Does Lupron shot needs to be done into the muscle? Did you experience the same problems?

Is there way to handle prevent this symptoms?

Thank you, Friends!

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FightCancer101
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26 Replies
mrscruffy profile image
mrscruffy

I take mine in the stomach, no problems

in reply to mrscruffy

Not Lupron Depot. It needs to be injected into a large muscle.

mrscruffy profile image
mrscruffy in reply to

Not true, can be given subcutaneously for Prostate Cancer. I choose stomach injection so as to avoid workout pain later.

in reply to mrscruffy

So you use Eligard version, that can go subq.

Lupron Depot (Brand) must go in a muscle.

mrscruffy profile image
mrscruffy in reply to

Taking Lupron brand. Mayo and other sources say subcutaneous or intermuscular. Been doing it for 7+ years now. I know i am being billed for Lupron

FightCancer101 profile image
FightCancer101 in reply to mrscruffy

So you do injection in the stomach to avoid workout pain. Is this documented somewhere that hip muscle injection might cause pain or injury after workout? That's what I feel happened with me.

Hohman profile image
Hohman in reply to FightCancer101

My Lupron Brand was always given in my Ass...but when they switched me to Eligard brand it is now Stomach. I always felt like i was kicked by a horse with Lupron for about a day after. Eligard has a slight burning sensation in my stomach but only for a small period

mrscruffy profile image
mrscruffy in reply to Hohman

Never had a bad reaction to the meds

mrscruffy profile image
mrscruffy in reply to FightCancer101

not injury but injection pain from the damn poke to the muscles. Not sure if injury could be in play but wouldn't surprise me

in reply to FightCancer101

I waited a few days after before resuming squats.

fireandice123 profile image
fireandice123

I’ve had the shots in my hip, at the very top of my hip just below my waist. And once in my arm. I far prefer my hip, No pain there, neither during the injection nor after.

in reply to fireandice123

Same here, upper glutes. Alternate sides.

Kaliber profile image
Kaliber

I’ve had 20-25 lupron implants …all in the alternating buttocks.

Starting with my very first Eligard injection nearly 9 years ago, I have always been injected in one or the other upper arm. Not a problem, yet.

Jake2021 profile image
Jake2021

Lupron, just below waist between glute and hip, alternating sides, sometimes sore for 24 hrs after but never more. Nothing to affect a workout.

Boywonder56 profile image
Boywonder56

It has to do with the injector...most dont care...ive had both lupron in butt and now since the grate hoax eligard in belly...the injection is suppose to take 45 seconds....the faster they do it the better chance for a lesser outcome...the doc..ive been left with bruises / soreness for days or barely noticeble after effects when done with care....

warrior22 profile image
warrior22

Lupron is given into subq fat as a " bolus " meaning small pocket right under skin of thick syrup like consistency. Not ever seen or gotten it IM.

Clays711 profile image
Clays711

My guess is that the nurse hit your Sciatic nerve. The nurse can find it with finger pressure before giving you the injection.

ShipModeler profile image
ShipModeler

I had a similar reaction. My hip pain lasted a week. My Oncologist suggested I switch to Eligard in the abdomen. That is how I have taken my last three injections. Aside from the brief needle stick I have experienced no reaction or discomfort.

TTJJ1 profile image
TTJJ1

I have been on Lupron for six years, injection always in the butt area below the waist line. I alternate each side for each injection. I had one injection in the stomach that caused a hardness and discomfort that lasted over a month. All other were in the butt area. I found that if you massage the area before the injection, you will have less pain. Since I have been messaging the area I will generally feel some very mild discomfort for a day or so, nothing that has caused me not to exercise the next day (3 mile run every morning).

alperk profile image
alperk

I get mine in the stomach fat. No burning pain IF DONE SLOWLY. I caution the nurse every time to go slowly. They love being told how to do it

SteveTheJ profile image
SteveTheJ

I have always had it in the butt and they keep track of which butt they inject it in. Right one time, left the other. Transient pain, no lasting pain.

Oldie68 profile image
Oldie68

Same here, had about 6 or 7 Lupron injections in buttocks, alternating left and right. Never had a strong pain, just a soar spot for a couple of days. As an alternative a shot in the arm is possible but I don't want to try it, for now. It's like in software: why change it if it works?

northshoreguy profile image
northshoreguy

Maybe off topic, but have you thought of switching to Orgovyx. Much shorter time to normality and don't have to worry about injection problems.

Yzinger profile image
Yzinger

my last shot (2nd shot) was in left shoulder (1st was right shoulder). Anyways, that shoulder was messed up for couple days. In fact night #1 was awful - didnt sleep a wink. I will do buttock next time.

j-o-h-n profile image
j-o-h-n

For those who care, my first Lupron injection was on 03/18/2008 (in my stomach) all other continuous injections up to including last month 10/06/2023 have been in my left cheek butt. No issues with the injections.....(except they call in those beautiful nurses to view my naked butt - I sort of like that)...

Good Luck, Good Health and Good Humor.

j-o-h-n Saturday 11/18/2023 7:30 PM EST

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