Rise in PSA after Radiation

[spolyu]

I had radiation to my right hip. The Ro could see that the Radiation was effective. I was advised to stop taking all antioxidants. during Radiation treatment.

A month ago my PSA was 21 and now it’s at 37. I am disappointed. I am currently on Ereleada. . My theory is that lack of taking the antioxidants may have caused the jump. In fact the Mo and Ro said the PSA from the radiation. should decrease.

I had to stop taking Xtandi due to a side effect of a rash. The irony was that after taking for a week the PSA decreased. I have been on the new medication Ereleada for about a month and a half and it increased a lot.

Does anyone have any suggestions?

Thank you

[Fightinghard]

radiation can cause temporary increase in psa level. As malignent cells die they release psa.

Wait a month and then recheck psa.

If xtandi was working for you, ask your mo if a low dose (5mg) daily prednosone might help take care of the rash. Or try 1/2 normal daily dose.

[spolyu in reply to Fightinghard]

Thank you very much for your response. I did suggest to mo to lower the dose. The mo indicates that the skin could come off.

I will talk to mo again about this.

Thank you

[Rocketman1960 in reply to Fightinghard]

I am in total agreement with this approach. The key to Xtandi is to use the lowest therapeutic dose that is effective without destroying QOL of the patient. IMHO.

[spolyu in reply to Rocketman1960]

thank you for responding

[Benkaymel]

I'm on Xtandi and currently in the middle of a 6 week course of RT to the prostate and a bone met. Had my PSA tested after the first two rounds of RT and it was about 30% up on the previous month. I'm hoping that is a temporary rise during the course.

[spolyu in reply to Benkaymel]

Thank you very much

[Tall_Allen]

Glad you stopped anti-oxidants. Not only do they interfere with radiation, they prevent the immune system from killing cancer too. Radiation initially releases a lot of dead cells into the blood serum, raising PSA.

[spolyu in reply to Tall_Allen]

Thank you very much

[Hidden in reply to Tall_Allen]

How about taking tomato paste while on radiation? That is natural and not a pill form.

[Tall_Allen in reply to Hidden]

Eat as much tomato paste as you like.

[tuta1960 in reply to Tall_Allen]

Dear TallAllen. Please help me. My father îs on Xtandi, Xgeva, Eligard and he was quite tired (because of Xtandi). We decided to help his body With some arginina. After a few days he feels much better. Is it wrong to take suplements? Can it interfere the treatment? I was thinking about Vit C, i have heard about curcumim s results but i am affraid not to do something wrong. I know u have an answer for me, better knowledge. Can u please help me?

Thank U! Wish u all the Best!

[Tall_Allen in reply to tuta1960]

Arginine is an amino acid, and is not harmful unless he takes so much that it replaces other amino acids.

Oral Vitamin C is an antioxidant and should be avoided in large doses. Eat citrus, red peppers, strawberries or cruciferous vegetables every day instead.

Curcumin can interfere with PSA tests:

prostatecancer.news/2019/04...

[tuta1960 in reply to Tall_Allen]

Thank you! I knew u will have an answer for me! Wiah u all the Best!

[tuta1960 in reply to Tall_Allen]

Sorry, but I must ask you something else. My father drinks 100 ml of aronia juice everyday. Now I realise that aronia îs an antioxidant. I sure hope it didn t make it worse. His psa started raising after 11 months (since he discovered pca and started eligard and had 6 docetaxel). Now he s on Xtandi. I hope we didn t harm him this aronia juice. Now we re waiting for his genetic test. His father, uncle, cousin ... The all had prostate problems / cancer but later than him.

Thank you, TA !

[Tall_Allen in reply to tuta1960]

Food and drink is fine. Only problem is supplements.

[Derf4223]

Tall_Allen, there are so many ways to intake antioxidants -- naturalhealthtechniques.com...

It seems like it would be very difficult to zero them out. What would be the types of antioxidant intake relevant to RT? Are they a problem thereafter during ADT+Abi phase? Thanks

[spolyu in reply to Derf4223]

fish oil, vitamin C, vitamin D, vitamin E, and all antioxidants. we could not understand it either.

we were told that I can resume taking everything again after a few days that the treatment is completed

[Tall_Allen in reply to spolyu]

Why take them at all? They interfere with normal bioregulatory mechanisms that control cancer.

[spolyu in reply to Tall_Allen]

Thank you very much

[TC007 in reply to Tall_Allen]

This guy is against anything that's Natural...he is all about chemicals in ur body. Tell him about Pacific Bark tree and he will say No to that but will happily recommend it as Chemo.. Will say No to anything that's not "proven" but will encourage you to take part in clinical trials with 95%+ failure rates....sheer double standard!

[Tall_Allen in reply to TC007]

Why is "natural" good? It is "supplements" that add toxic chemicals to your body - a body debilitated by cancer. What makes you think they are safe and effective? When a natural product is used as a drug, it is refined to get rid of all the toxic chemicals that cause worse side effects but don't increase efficacy. Plus, you know exactly what you're getting in each dose, and you know what the drug interactions will be.

Clinical trials are often the only way to get unapproved drugs early. Patients are well-informed about the potential risks and potential benefits, and are very closely monitored. Also, it's a good way to help others.

[Tall_Allen in reply to Tall_Allen]

"he is all about chemicals in ur body." In a simple lettuce leaf, there are millions of chemicals! Cells are chemical-production factories. Most of those chemicals occur in such small amounts that they have no effect in humans, and our guts and microbiomes screen out the one we don't need and allow the ones we do need. If you eat food, you take chemicals. The problem occurs when people take supplements which concentrate those chemicals to amounts never found naturally, and our bodies have not evolved to deal with.

[caysary in reply to TC007]

Make sense of your argument a little at least bit. Cancer cells are evil. They are intelligent, evasive and will trick your immune system to submission. You really think anti-oxidants can overpower them? TA makes more sense in his sleep than you awake.

[Tall_Allen in reply to Derf4223]

The issue is supplementing antioxidants, not antioxidants that are part of the foods we eat. Our bodies are good at determining how to use anti and pro oxidants from the foods we eat. Your body does not need extra help from you.

[chefjlu in reply to Tall_Allen]

Thank you, I tell people the same thing. Eat a variety of foods and your body will use the natural intake accordingly. Some might be interested in a recent research project that I have been in discussions about. It shows that in some cases, supplementation has little to no impact on the system. One problem being who is testing and certifying the amount in something. By eating a large variety of foods with natural antioxidants other nutrients and phytochemicals are there and they work in conjunction. Supplements do not contain these.

[spolyu in reply to chefjlu]

thank you for responding

[SteveTheJ]

Please define and describe "anti-oxidants"; seems like every other thing is called that.

[spolyu in reply to SteveTheJ]

vitamin C, Foods:Acai BerriesAlpha Lipoic AcidAstaxanthinBeta CaroteneBilberryBlueberriesCo Q-10CucurminCysteineGinko BilobaGlutathioneGrape Seed ExtractGreen TeaHydrogen Peroxide (H2O2)MangosteenMelatoninOligomeric Proanthocyanidins (OPC’s)Olive leafPolycosanolPychnogenolResveritrolSeleniumSuperoxide Dismutase (SOD)TurmericVitamin AVitamin CVitamin EZincAcai Berries:  en.wikipedia.org/wiki/A%C3%... Lipoic Acid: Best Bet Food Sources– Meat

The RA never mentioned it 2 years ago, when other Radiation was done

[SteveTheJ]

Thanks

[Hidden]

My husband also had consistently rising PSA while taking Erleada. He never did the antioxidant thing so we know that was not the cause . Rather his cancer was actively spreading again.

[spolyu in reply to Hidden]

Thank you for responding

[Buddy74]

My beloveds Prostate cancer has come back after 12 years and he took the vaccine. He had high dose radiation back then w hormone therapy and beam radiation. It has spread to his lymph node and they suggest hormone therapy for the rest of his life...he's 79 and not sure they can radiate the lymph because its so close to his colon. So I got him on that frozen pulp from the Soursop fruit and I make a tea with its leaves. Evidently if you eat this delicious fruit you never get cancer. Its grown in the tropics. Then I started him on Ivermectin and if we don't see his numbers drop then we go to the big guns which is Fenbendazole...or Panacur..yes its a dog dewormer but from all my research it is parasites and worms that cause the cancer in the first place. Thankfully he's open to try it should he have to. Google Joe Tippens story and read how he cured himself of stage 4 cancer. God bless you and put you on the right path for you.

[scottward in reply to Buddy74]

Google IP 6 with inositol

[spolyu in reply to scottward]

Thank you