Hobie14 : Seventy four years old... - Advanced Prostate...

Advanced Prostate Cancer

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Hobie14

Hobie14 profile image
20 Replies

Seventy four years old retired commercial painter like to hear some ideas about handling. psa 6.8 Gleason 4+3, waiting on decipher test.

Can I wait until September treatment?

Thanks

MO wants to start me ADT followed by.

RO recommended, RapidArc VMAT with daily CBCT for IGRT

Dimensions: 4.2 x 3.1 x 4 cm corresponding to a volume of approximately 27.8 cc. Post biopsy hemorrhage: Absent

Peripheral zone:

Lesion #1:

Location: left mid posterolateral peripheral zone

Procedure Note

Greatest dimension: 1 x 0.5 x 0.5 cm (series:4; image:13)

T2-WI: Circumscribed, homogeneous moderate hypointense focus/mass (score 4)

DWI/ADC: Focal hypointense on ADC and/or focal hyperintense on high b-value DWI (score 3)

DCE: Positive

Extra-prostatic extension: Equivocal (capsule contact > or = 1.5 cm OR capsule irregularity or bulge) PI-RADS assessment category: 4

5/13 cores involved

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20 Replies
Tall_Allen profile image
Tall_Allen

If your Decipher score is low, IMO, you can wait until September.

Hobie14 profile image
Hobie14 in reply to Tall_Allen

Thanks

ron_bucher profile image
ron_bucher

Keep in mind that biopsy is just a sampling and often underestimates the actual Gleason. My biopsy was 3+4 and my prostatectomy pathology a few weeks later was 4+3.

Linebacker75 profile image
Linebacker75 in reply to ron_bucher

same with me. 4+5 from biopsy then 5+4 from surgical pathology.

maley2711 profile image
maley2711 in reply to ron_bucher

and can be downgraded after RP pathology!! Goes both ways I believe?

Hobie14 profile image
Hobie14 in reply to maley2711

Thanks

ron_bucher profile image
ron_bucher in reply to maley2711

Possible but not as probable.

ncbi.nlm.nih.gov/pmc/articl...

Hobie14 profile image
Hobie14 in reply to ron_bucher

Thanks

Hobie14 profile image
Hobie14 in reply to ron_bucher

Thanks

NecessarilySo profile image
NecessarilySo

Waiting allows the cancer cells to grow,

Hobie14 profile image
Hobie14 in reply to NecessarilySo

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Derf4223 profile image
Derf4223

You probably heard your PSA was too high about 4-5 months ago, and presumably you are not on firmagon yet, so your cancer has exponentially gotten worse since then. For myself, with what sounds a lot like you (aggressive 3+4/4+3 Gleason, PSA at initial blood test 25, then 30 just before firmagon commencement), I did not add any delays to the run-up to firmagon and RT. My catch phrase from the DRE onward has been "suck it up buttercup."

Hobie14 profile image
Hobie14 in reply to Derf4223

Thanks

Tony666 profile image
Tony666

on waiting, you can probably wait a month or two before starting treatment. Studies have shown that prostate cancer is slow growing and a small wait won’t make a difference. That said, don’t wait too long.

on treatment, at age 74, unless you are in top health shape, my guess is it’s not surgery. It’s major surgery and after 70 it’s harder to recover. Most likely, with 4+3 and possible EPE, your best option is radiation w some adt (not sure of the best length of adt). But take your time, get lots of opinions and then make an informed choice. Make sure you are not steamrolled into doing something you are not comfortable with

Hobie14 profile image
Hobie14 in reply to Tony666

Thanks

babychi profile image
babychi in reply to Tony666

totes agree!

Zzzgott profile image
Zzzgott

Why wait? Nip it in the bud. My 4+3/12PSA had extensive tumors thru out my spine, ribs etc

groundhogy profile image
groundhogy

start studying. You are entering an extremely disfunctional industry. 

After you study, and know the odds of cure for every treatment pathway, you might notice the urologists quoting much different numbers to you. I found that the docs would tell me it was my choice which way we would go, but then they would quote inaccurate statistics that if followed, would drive me to their preffered pathway.

Another mistake i made was to throw one hook in the water at a time. I was sure the docs would help me. But if they don’t, you have to throw another hook in. This causes delays. Delays allow cancer to morph its dna or advance. You may throw a bunch of hooks in at the beginning. Parallel not series. Its your life.

Go here...prostatecancerfree.org/comp...Look at these three charts til you know them by heart. If you have trouble find someone to help you read them. (Hint: draw a dot on the endpoints of each elipse and draw a line through the dots. Easier to read). 

So spend 4-8 weeks studying papers and books on this subject.

babychi profile image
babychi

Agree with Tony 666. Diagnosed 2017 at 71. Radiation and adt have worked for us. So far. Diet is now organic. No booze. Lots of exercise. He is fit and fabulous. Research is key. Surgeons just wanna do surgery. 💜

Hobie14 profile image
Hobie14 in reply to babychi

Thanks

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