Theacrine - Potential Caffeine Alternative with Anti-PCa potential?

[jazj]

I have a very mentally intense job and only drink a cup of coffee a day and maybe occasionally in the afternoon a supplement 100mg Caffeine + 100mg Theanine.

It's more focus I need than energy (almost as if I have mild ADHD.) So I don't take a lot of supplements since my surgery and I'm still undetectable but understandably very leery at taking anything (there's a ton of stuff out there) other than stuff with a well-established safety record like Vitamin D.

So I ran cross Theacrine which is similar to Caffeine but without the energy kick and the subsequent come down. Unfortunately there's little data except in vitro it does appear to attenuate epithelial mesenchymal transition (EMT) at least in breast cancer cells and I did further reading to confirm EMT is also a component in Prostate Cancer Cell progression it appears. So that's encouraging. Just wondering if anyone else looked into Theacrine and what their thoughts were?

pubmed.ncbi.nlm.nih.gov/311...

More info

researchgate.net/publicatio...

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[Derf4223]

I'm asking my MO about L-theanine.

[Derf4223 in reply to Derf4223]

My MO said: "Should be fine. It is not well studied living, human subjects, so it is tough to say if it interferes with meds."

I started taking 200 mg L-Theanine yesterday. Brain fog / drowsiness was minimal. I had a little trouble falling asleep (I took it with lunch yesterday, and with breakfast today.) So far so good.

The best part is that the carb cravings I had before it are gone. It makes me wonder if carb cravings on ADT/abiraterone are why men have weight gain problems.