RADIOTHERAPY to prostate. Nearly finished chemo/doxetaxel, am on ADT injections PSA 0.11,

[Mrtroxely]

oncologist recomends 6 radiotherapy to the prostate in march.

Gleason 9, PCA mets in hip DX July ish.

.Would any one mind giving experience and opinions on taking radiotherapy.

I've said yes, but know it's 50/50 for any benifit, but realise there's a possible price to pay with side effects short and long term...

Thank you, it's appreciated and this site has helped where health proders haven't.

[Hopeful129]

my husband finished chemo in August, part of triple therapy with Daralutomide. He is half way through 34 radiotherapy sessions to prostate and pelvic area. He manages to play tennis and work everyday ( sessions are mon-Fri) and so far no fatigue but side effects are diarrhoea and irritated bladder. It feels slightly worse than the chemo as so relentless and side effects are unpleasant. Exercise helps him and he’s doing some hyperbaric sessions during and after. Oncologist believes in the benefit of blasting the mothership when it’s low volume. He had 3 small bone mets but quite a lot of lymph node involvement in pelvis and chest

[Mrtroxely in reply to Hopeful129]

Thank you

[Poowater]

50/50 - seek out where this originated from. I was told the same. Having regard to damage to the bowel and future likely cancers I would say no. ADT is more than sufficient.

[Vangogh1961]

I felt there would be some benefit for essentially debulking the prostate. I enrolled in the EXTEND trial at MD Anderson. I was randomized into the arm that did pelvis and my one spot on T7. Since the other arm was pelvis only, I wasn't too concerned about the randomization process. I was de novo oligometastatic and wanted to do as much as possible in the beginning. I had some increased frequency during and after, but now a year later, I am only up once a night and actually sleep through some nights.

[StephH72]

this is a decision that’s not easy to make so I feel for you. I’m wondering if the radiation oncologist told you the results would be 50/50 though or where that info came from? I’ve been trying to find studies that could give my husband some % numbers as well (he’s gleason 10 with lymph node spread).  And he’s a an engineer who likes data to make decisions Tall_Allen any input?

[Tall_Allen]

Prostate radiation ("debulking") is only beneficial is there are 3 or fewer bone metastases on a bone scan.

prostatecancer.news/2018/09...

[AatBR]

I have low volume PC with 3x bone mets. I am on ADT (prostap), had 6 sessions of docetaxel and have had RT to prostate and my 3 bone mets. I also had a SpaceOar fitted to reduce any collateral damage to bowel. I had some side effects in terms of bowel issues for about two weeks but carried on working throughout the treatment and after. Now 6 weeks post RT I feel fine (apart from minor fatigue). PSA is 0.14 currently.

[Kittenlover50]

bill had 37 after chemo then 6 mo of adt and zytiga, had meds during and for a year after. Had no problems during other than 2 days loose bowels the 5 th week. No issues with bowels, urine after. No fatigue during. Has been non detectable no evidence disease 6 years, no cancer meds or treatment 5 years. He did start falling a year later, couldn’t walk stairs normally or lift leg to tie shoes. Neurology determined it was a case of Lumbar plexopathy, the wearing away of the mylion sheath around a nerve secondary to radiation. Radiology disagreed. Have several infusions of like solumedrol, and did return to almost baseline.