if I am stable following treatment should I consider volunteering for this vaxinr?

[Brysonal]

First-in-human Study of OVM-200 as a Therapeutic Cancer Vaccine

Though I got covid twice despite having had the Oxford uni developed triple jab!

Maybe to discuss with MO if my PSA continues undetectable and bloods are recovered 100%. My red blood count was still slightly low last month.

[Brysonal]

identifier

NCT05104515

[AlanMeyer]

Hello Brysonal,

Personally, I'm a fan of clinical trials. As a trial participant you have a chance (admittedly it's only a chance) of significant benefit from the trial treatment and you have an opportunity to benefit a larger cancer community - in this case the initial benefit can be for prostate, non-small cell lung, and ovarian cancer patients. ( see: clinicaltrials.gov/ct2/show... ).

The trial that I entered was for a treatment (MRI guided high dose rate brachytherapy) that turned out to work, but the benefit it offered was soon surpassed by other treatments, so it didn't help many people. But the ideas behind it were good and needed testing. Even though better results were obtained by other treatments, there were lessons learned that may have helped a larger community of researchers and patients.

One thing that happened in my trial was that I met some very fine doctors. They were scientists as well as radiation oncologists. They were good at explaining things. They tested me exhaustively (they needed to understand as much as possible about all patients in the trial) and learned more about my cancer than my local doctors had. They followed up on anything that happened to me that didn't seem right.

There are risks when testing new drugs but at least the mice came through it well or it wouldn't be tried on humans.

Best of luck with it.

Alan

[Brysonal in reply to AlanMeyer]

yes the mice must have coped!

At least one human too according to this report and hopefully a few more ( being patient 1 must be a worry!)

oxfordvacmedix.com/first-pa...

PSA test in with the less than sign again so three months of undetectable. Red blood count still slightly under norms though told overall my bloods are good.

I think I will enquire as these things take time and who knows it might work! Or I may be rejected or just decide it’s not for me as really not hero type!

[AlanMeyer in reply to Brysonal]

Sounds like a good plan.

[Seasid in reply to AlanMeyer]

which phase was your clinical trial?

[AlanMeyer in reply to Seasid]

It was a Phase II trial.

[Seasid in reply to AlanMeyer]

this one is phase I to test for toxicity

[Hidden]

Good luck. Although a tough decision, I echo Alan. My Phase 2 clinical trial in 2004, saved my life though others did not have equal result. I too had the benefit of the best in academia and research.

GD

[Seasid in reply to Hidden]

this trial is a very small phase one clinical trial to test toxicity

It would be like compering apples and oranges. (Phase I to phase II)

Have a look at the car-t phase I clinical trial results. I believe only very desperate people need to apply. Definitely not people who didn't exosted other options or like me who still have standard of care first.