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Study Finds: Drug typically used in cancer therapy emerges as powerful anti-aging remedy

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Stud

y Finds: Drug typically used in cancer therapy emerges as powerful anti-aging remedy

Rapamycin is a cell growth inhibitor and immunosuppressant that people normally take while undergoing cancer treatment or after receiving an organ transplant.

A team from the Max Planck Institute for Biology of Ageing, however, notes that the drug is also a promising anti-aging formula.

Studies involving animals have found that low doses of rapamycin can extend life by preventing age-related changes in the intestines. Until now, however, scientists have looked at this drug as something patients would need to take for the rest of their lives.

Study Finds: Drug typically used in cancer therapy emerges as powerful anti-aging remedy.

studyfinds.org/rapamycin-an...

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cesces
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cesces profile image
cesces

Thanks.

It sort of sucks that it's an immunosuppressant though.

Does that concern you at all?

Scott1963 profile image
Scott1963

Thanks for your compendium. I have been taking Rapamycin for a year. I dose 20 mg every two weeks. Feeling great. BPH doesn't give me any trouble now. We'll see how my PSA isnext month.

cesces profile image
cesces in reply to Scott1963

Rapamycin reduces blood pressure?

MateoBeach profile image
MateoBeach in reply to Scott1963

That’s a pretty high dose and possibly in immunosuppressive territory. Low dose such as 2 or 3 mg once weekly showed improved immune response, not immunosuppression in elderly adults response to influenza vaccine. I take 3mg weekly.

cesces profile image
cesces in reply to MateoBeach

Thanks

Very interesting

Scott1963 profile image
Scott1963

5% of the population has an infection. Immediatelytake a Zithromax.

Medline profile image
Medline

Aspirin was the most potent life-extension agent when data for all model organisms was combined, more so than rapamycin or metformin.

link.springer.com/article/1...

cesces profile image
cesces in reply to Medline

"We found that, when data from all organisms studied were combined for each compound, aspirin resulted in the highest percent increase in average lifespan (52.01%),

followed by minocycline (27.30%),

N-acetyl cysteine (17.93%), nordihydroguaiaretic acid (17.65%)

and rapamycin (15.66%), in average.

We showed that minocycline led to the highest percent increase in average lifespan among other compounds, in both

Drosophila melanogaster (28.09%) and

Caenorhabditis elegans (26.67%),

followed by curcumin (11.29%) and

gluconic acid (5.51%) for D. melanogaster

and by metformin (26.56%),

resveratrol (15.82%) and

quercetin (9.58%) for C. elegans."

So very interesting

Purple-Bike profile image
Purple-Bike

If you take Casodex to avoid resistance to rapa, would you mind telling dose and frequency?

Purple-Bike profile image
Purple-Bike

Thanks. I had some wbc lowering after low-dose rapa, but it may have been co-incidental and will restart. Will aim for one mg plus two grape fruits = 3mg weekly.

GeorgeGlass profile image
GeorgeGlass

who prescribes this for you? Do they say it is for general health, or to fight cancer?

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