Scot inhibition study

[Mascouche]

This looks like a potential breakthrough. Apparently the ketones from fasting have a different behaviour on cancer than the ketones from a diet.

researchgate.net/publicatio...

[Faith1111]

If you would like more information on fasting then look up Dr. Vaulter Longo. He is an Italian scientist and a leading expert on the topic. His work is very interesting and he does talk about the effects of fasting on cancer. valterlongo.com/

[Mascouche in reply to Faith1111]

I bought his longevity diet book a few years back. I have already done a 18 day water fast in March 2020 and really appreciated the rejuvenation I felt in the weeks that followed. It also cured me of my cat allergy which still has not come back so far

[Faith1111 in reply to Mascouche]

18 days? Wow good for you!! I only did 24 hours and followed it up with a hot fudge sundae!! I was hoping if I read his books I would get benefits through osmosis!! Nice accomplishment for you!!

[dhccpa in reply to Mascouche]

I've done 9-10 days. Maybe I should give it another shot.

[Spyder54]

Mascouche,Im sure you are trying to help. No doubt. Your Research piece is above my pay grade. I tried to stay with it. Scanned down to summary, it lost me again. We that have APCa come from many backgrounds. We cannot all be Scientists. Can this be put into a read for the common man?Mike

[Mascouche in reply to Spyder54]

It was originally thought that a ketogenic diet could help starve cancer based on the premise that cancer is supposed to be feeding from sugar /glucose. Then that theory fell short when they discovered that prostate cancer can also turn ketones and protein into glucose if it needs to. Now they have discovered that unlike ketones from diet, ketones from fasting could have an impact on starving cancer, provided that they are used with some other things like r-lipoid acid and other listed in the article. Time will tell if this pans out or if it was a pipe dream. One of the people paying for the study is Guy tennenbaum who had stage 4 cancer with metastasis to the bones and looks like he has been free of tumors and metastasis for about two years. His whole story since he was diagnosed can be found on YouTube where he has produced about a video almost every day during the first two years of his fight with all of the up and downs of his hopes, defeats and eventual success.

By the way, please do not take what I have written as the fully accurate science. I may be a data analyst but I am by no means a scientist or a doctor.

[Spyder54 in reply to Mascouche]

Mascouche, another thought (actually 2 thoughts) on difficulty reaching a ketosis state while on Prednisone. An Oncologist in Orlando told me that many of his patients are on Abi/Zytiga with NO PREDNISONE, and asked me to slowly from 10mg down to 5mg. I did this over 3 weeks, no problem. Perhaps on lower dose, ketosis could be reached? I will find out and let you know. Secondly, many of the guys are doing Modified BAT, with surpa physiological Testosterone for 3 months followed by ADT to castrate levels for 3 months. This could be the time to fast during the 3 month ADT Break? Mike

[Mascouche in reply to Spyder54]

This guy should explain it better than me youtu.be/wiGVsUtCZwI(Not working as expected?)

[Spyder54 in reply to Mascouche]

THANK YOU MASCOUCHE !!Yes, watched until the end. I am a Big Fan of Dr Thomas Seyfried of Boston College, lowering Glucose and Glycogen levels (although I have not hopped a plane to go up and volunteer as a study of N=1 or 2).

I believe this can assist many of us. I will add some version of fasting to my routine. I would be curious if staying on the Triplet ADT would turbo charge the fasting approach. I will also subscribe to his YouTube channel. Much appreciated. Hope many will watch!

In my opinion, “it all works, but nothing works well”, but then again, no stone unturned. This could be a quantum leap forward.

Much appreciation, Mike

[Spyder54 in reply to Spyder54]

Correction: Lowering Glucose and Glutamine (not Glycogen) levels.

[Currumpaw]

Nice post and a recent study. May 2022. Not two years ago. Or four years ago.

I have been practicing intermittent fasting for years.

Currumpaw

[Mascouche in reply to Currumpaw]

I have done long fasts of 3 to 5 days and one very long of 18 days between 2016 and 2020. But since I began adt in 2021 I have not been able to achieve ketosis which is when you begin to enjoy the benefits of the fast. It recently dawned on me that it is a likely because of the prednisone that I take with the Abiraterone. Prednisone raises the cortisol and cortisol increases your glucose levels even if you do not eat carbs. So I have made my peace with the situation and I know that I will be waiting until my treatment is over in April 2023 before I can once more get something out of fasting.

[Mascouche]

What is interesting in the case of Guy Tennembaum is that after each scans and each psa test and blood work he shares the medical results publicly through links in his videos. So we were able to see when he was getting worse and when he was getting better as he tried different things. He did not reject SOC but had been sent home after he was told "there is nothing we can do for you. Go home and enjoy the two years you have left to live". That is when, in despair and with nothing to lose, he began to try different paths. A few years later he appears to be cured but not 100% certain as to why. That is when he, Dr Berg said others began funding studies to try to pinpoint what it was that worked. He might remain a unique success that can't be replicated or he might be a catalyst for a new solution. Time will tell I guess.

[Spyder54 in reply to Mascouche]

Mascouche, I am a believer, that the Power of the Mind is unchartered. A portion of his success could be that he deeply believed it was working, and his bodies immune system took over? I believe that Mitochondria, contained in every cell in our body, and which gives us energy, is part of the solution. If Tennebaum somehow awakened his Mitochondria, perhaps this is part of the answer. Mike

[Mascouche]

Here is another link for the research on SCOT inhibition: jscholaronline.com/full-tex...

[Purple-Bike]

Mascouche,

I don´t question ketones from fasting having a better effect on cancer than ketones from food, as per the link you provided.

However, whereas the following article indicates that autophagy, typically achieved by 2 - 4 days of fasting, appears to play a protective role to suppress malignant transformation in the early stages in cancer, it supports and enhances tumour growth in the advanced tumour. From "Is targeting autophagy mechanism in cancer a good approach? The possible double-edge sword effect" by Su Min Lim et al, Cell & Bioscience volume 11, 2021 "In advanced stages of tumor development, .......starvation conditions generate signals promoting tumor invasion and metastasis".

One obvious question is the definition of "advanced tumour". When I look at your profile, it seems you have not had that. As for myself, I had a single solid met that was spot radiated and for now cancer is apparently quiet.

[Mascouche]

I can't say if it is different in behavior before and after cancer. I know Guy Tennenbaum who had mets to the bones has done several long fasts of 10 days+ and he no longer has cancer at all. He might be a special case though I became aware this very morning of another similar case which is discussed in this video: youtube.com/watch?v=YzPrxku...(Not working as expected?)

Best of luck to you whatever you choose to do.

[Verde2]

Mascouche, I just now joined healthunlocked, do you have any further info on longer-term fasting since your post 7 months ago?