Benefit of "triplet therapy" confirme... - Advanced Prostate...

Advanced Prostate Cancer

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Benefit of "triplet therapy" confirmed with enzalutamide too

Tall_Allen profile image
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An updated, subgroup analysis of the ENZAMET trial among newly diagnosed men with metastases confirms the triplet of ADT+enzalutamide+docetaxel increases survival. 5 year survival was 60% for the triplet vs 52% for ADT+docetaxel. The benefit was especially pronounced in the first 2 years of triplet therapy in men with high volume metastases.

urotoday.com/conference-hig...

Enzalutamide (Xtandi) joins abiraterone (Zytiga) and darolutamide (Nubeqa) in showing usefulness in triplet therapy added to docetaxel and ADT.

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Tall_Allen
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garyjp9 profile image
garyjp9

thank you, TA

Farn profile image
Farn

So am I reading this right in that there is no benefit to the triple therapy approach for low volume men if using Enzalutamide ?Thanks for the signpost

Tall_Allen profile image
Tall_Allen in reply to Farn

There is more benefit in high volume men, but there was some benefit in all men.

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