After 8.5 months on Lupron and 6 Months on Zytiga. PSA reached undetectable levels.
Been off Zytiga for 14 days and liver enzymes have fallen back into normal range. Conversation with MO tomorrow , will see how and when he wants to restart it.
Life is good
Next step- radiation therapy.
Congrats sending good vibes...
Who's a lucky boy 😀
Excellent result big fella.
Thanks, I have had a very luck life. How are you doing now?
I shall find out tomorrow.
PSA went from 28 to 16 a few weeks ago. Hoping for a sub 10. If not, well I will revaluate approach.
Good for you Scout. Let us know what the new plan is.
Great to read!
It took you a while to get to undetectable, and there is research out there showing that a gradual drop to PSA nadir tends to signal a better long term prognosis. So while your PSA is down, it looks like everything else is looking up. Enjoy!
Thanks, my read on situation as well.
I'm thinking you are in remission, and can now enjoy the healing.I'm so glad for you, Radiation,( burning), might not be needed as what is there to burn off?
🦋🌹🍏🥦
Hi Canoehead.I heard about that: slow and steady PSA decrease under Zytiga means longer prognosis. But I have hardly been able to understand the reason for that ? Do you have any source you can share on the topic ?
That's great news.And you still have your prostate and you haven't had radiation tx yet?
correct
Really good news and good for you . I hope you can ride this positive momentum and hang in there a long time buddy.
💪💪💪❤️❤️❤️
Thank you, my intention exactly.
Glad to hear good news! Wishing you the best. Let the killing begin!
Thanks
Now to ride it out for as long as we can ?? Some have for more than a decade. Fly low under the radar Scout ! ✈️
Good news is always good to hear in this group......
Excellent news
That’s very good Scout4 answers I’m similar situation with PSA !!
Radiation is not required if PSA is undetectable. Why go off Zytiga?
I have been thinking about this issue , I had an MRI on 4/20 that showed no cancer present, do you have any study or info to back that up.I have restarted Zytiga @250 mg.
No, just the fact that there is nowhere to radiate.
Congratulations, I've been on Zytiga, Lupron and Prednisone for about 4 years. In total 9 years of various treatments, only in the last two have I reached undetectable, but not as low as you.
I'm intrigued why you are not just going to continue as you are, it's a great result and if it's not broke, why try to fix it ?
All the best.
I'm assuming he figures he can at least try to cure it without taking ADT for the rest of his life, no?
Yes
Possible, but as far as I'm aware, there is no " cure " as such. Also there is the problem with the effects on Scout4answers liver, perhaps a reduction to 250 mg could be the way through. I'd be celebrating, great news for him.
that assumes the femur is actually a metastasis. it may very well not be.
Femur is not thought to be a metastasis by ROs who have viewed MRIs and PET CT scans.
But they will still radiate just in case. and call it palliative. Which looks shocking on the insurance report but better than not radiating it.
Good on you. 😃👍
Congrats. Great news.
Thats wonderful news , i hope it stays that way for many many years x
Great result
Great news. I’m so happy for your results. I pray they remain that way for a long time.
thanks
You did it right, congratulation!
Way to go Scout 4, thanks for sharing good news
HiVery good news .....thumbs up
Congratulations on the good news!
Some good news, Scout. Keep it up.
GD
Great results, I wish you continued undetectable results going forward
Huzzah!!!
GREAT NEWS GLAD TO HEAR THAT.I'm wondering what the next step will be.
Are you sure you need radiation?
👍
I am wondering this as well.
Just because the cancer is asleep doesn't mean a lot, does it? Why not pursue the course of radiation originally planned? Whole pelvic and prostate. Radiation to the femur "just in case." It might not be cancer in the femur and probably isn't but obviously you zap it anyway. I mean this radiation and everything either works or it doesn't but its definitely worth a try, seems to me.
Congratulations I'm on the same treatments four years now. I like you had Liver enzyme problems so my Doctor cut my Zytiga down to 750 mg three tablets and at first one and a half Prendisone to now one a day. My PSA has been 0.1 for four years now. Never give up Never surrender. Leo
I restarted Zytiga @ 250mg with low fat meal per MO
Scout are you still with Dr.Szmulewitz at U of C ?
I had a consult with him but have remained with my local MO for convivence
Doesn't get much better than this!
How about spontaneous remission 
I also had high liver on Zytiga. Went off for a month and went back to normal. Went right back up when I resumed. Had to switch and have been on the Ztandi Carousel for close to 2 years and PSI is <.1. Lowered the dose to 80mg to minimize side effects but still have the usual brain fog, fatigue, muscle loss, depression and joint pain. I wonder if it is the Lupron /Eligard, Ztandi or just old age? I'm on this treatment until resistance. No surgery or radation it has spread too far.
Glory to God! Reading your post and others have been so inspirational! Yes, I know every case is different but seeing so many are on the same regimen I am on and you are still here to talk about it is miraculous to me. I was diagnosed last year and my PSA has steadily dropped each appointment. I take Xgeva, Lupron, Zytiga, and Prednisone. Thanks again for posting! Long Live Us!
Great news, Scout. Keep on truckin' (Do they still say that in the US?).
Well Scout, I would try to concentrate on the great remission.Only you can decide if you want to do radiation.
LRV
That is great. Hopefully you can stay at that level. Keep playing tennis
If PSA is undetectable for over 2 years?
Husband thinks PSA undetectable means cancer is undetectable...I think not
Undetectable PSA
Now Undetectable PSA on BAT Regimen
Undetectable PSA but new bone uptake
