Short update on Lu-617 therapy

[MarkEmrys]

Well, now 9 days after 1st Lu-617 therapy. Some fatigue persists. No other side effects. Bone pain reduced by say 40%.

Scheduled for bloods in 12 days (3 weeks after infusion) to check kidney liver etc functions, including platelets psa and so on.

Cheers

Mark Emrys

[Ramp7]

Great news Mark. Keep it up. I'm scheduled for my 4th infusion in a couple of weeks. Just had blood work, cat and bone scans, cancer continues to shrink. From my brief experience, around the forth week after infusion my energy seems to improve. Latest PSA 0.22.

[MarkEmrys in reply to Ramp7]

Thanks — that’s good to know. Im having infusions every 6 weeks

[6357axbz]

Is this related to Lu-177

[MarkEmrys]

Yes. 177Lu-617; that is, the same.

[docbulldog in reply to MarkEmrys]

I missed what part of the world you are in, I hope I’m in line at University of Washington to start this treatment. The chemo, docetaxel did not do the job for me, my psa went up to about 60. Thank goodness I have no pain and such so I could handle that increase in PSA but I need to get into a treatment that’s gonna work. In the meantime I am being infused with the second line chemo. Best of luck to you Mark.

[MarkEmrys in reply to docbulldog]

Thanks DoCBulldog. Im in Cairns Australia. Having Lutetium in Brisbane. Second infusion onn9 June.

[Mischa1111111]

Very encouraging!!! Congratulations!!!!

[MarkEmrys]

Hopefully…

[Shooter1]

Great that stuff is working for you. Easing pain and shrinking mets must be wonderful... The Xofigo I'm on is supposed to work as well as the Lu177, but so far not so much. Pain somewhat better after radiation second go around but PSA didn't drop this time. Ra-223 is what I could get. PSA has been climbing through the last 3 mo. even with radiation and Xofigo. Up 100%. 60% , and 288% the last 3 mo. Last weeks blood work looked real good, the best in over a year, except for the skyrocketing PSA. Another infusion the end of May and then full scans in June to see what my mets are doing.. Wish me luck, the power of Prayer may be all I have left.

Has the shortage of the Lu177 effected you yet. Looks like the manufacturer has stopped shipping to UK and US. Only shipping to Europe from Spanish plant. Hope they get everything straightened out.

[MarkEmrys in reply to Shooter1]

Hi shooterThanks for the good wishes. Please accept my good wishes for you. I don’t know your history but there are many options now and some hope with newer research. My next infusion is some 4 weeks away. Have heard nothing about shortage in Australia but will check Monday.

Best

Mark

[MarkEmrys in reply to Shooter1]

Australian nuclear science and technology organisation produces Lutetiim so should be ok here.

[Clotter1 in reply to Shooter1]

Hi Shooter1,I’m told they begin manufacturing it in NJ in next few months. I’m going for second infusion in three weeks. After that I do another. PSMA. Still mild fatigue.

[Ramp7 in reply to Shooter1]

I was just notified by Dana Farber that Pluvicto production has some interruptions and my next infusion mat be a couple of weeks late.

[KocoPr in reply to Ramp7]

Hi Ramp7, are you in Boston area? I go to MGH, consulted with dr Daniel Roberts at DF.

[Ramp7 in reply to KocoPr]

I'm about 125 West of Boston in the NW corner of Connecticut. So happy to be associated with Dana Farber, very special organization.

[KocoPr in reply to Ramp7]

Yes, Boston has some great cancer hospitals. We are fortunate here.I am 15 miles north of Boston but will be going to NYC for trial

[Ramp7 in reply to KocoPr]

Hope all goes well.

[MarkEmrys in reply to Ramp7]

Thanks R

[d3is4me]

Mark Thanks for the update Great things are going well

[dmt1121]

Hope all goes well!

[MarkEmrys]

Thanks 🙏

[Lavender22]

Thanks for your update. Wishing you continued success with this treatment.

[KocoPr]

Thanks for the update Mark.What was your dose and how many more infusions are you getting?

Did you put ice around saliva glands or drink lemon water? Any affects on saliva?

[MarkEmrys in reply to KocoPr]

8.1 Gbq. Have only had one dose. Sipped lemon water. Nno probs with salivary glands.

[MarkEmrys in reply to KocoPr]

Sorry - up to six infusions each 6 weeks apart. After second infusion there is a PSMA/PET & FDG scans to see if it is working then decision made on continuation.

[shipoo]

Great news! So glad you are having success.Has anyone had Lutetium infusions without previously having chemo. If so, where was this done and what was your experience?

[j-o-h-n]

You're hitting the mark Mark..........

Good Luck, Good Health and Good Humor.

j-o-h-n Sunday 05/08/2022 7:09 PM DST