Hormone treatment: I was wondering, my... - Advanced Prostate...

Advanced Prostate Cancer

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Hormone treatment

androgeen profile image
22 Replies

I was wondering, my father just passed away. How long treatment with hormones a male body could endure? Saw over the years his mussles reduced, his sterngth dwindle. And his lust for life he always had reduced to zero. His last medication enzalutamide caused a mayor collaps of his endurance.

These times are the most difficult. Rememberance causes anger and tears

Best whishes to all for the coming days. And treatment will be succesfull

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androgeen
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22 Replies
Darryl profile image
DarrylPartner

Condolences

Very sorry that your loved one saw his life so rudely interrupted by PCa and the treatment, which likely gave him extra life, but not good quality life. There are no good answers.

Metaldraft profile image
Metaldraft

I’m so sorry and my deepest condolences. Myfather my best closest friend he passed tragically but his laughter his love for life and all the good times that will always be eternal and shre with my grandchildren My heart is with you .May find your peace in time

j-o-h-n profile image
j-o-h-n in reply to Metaldraft

You're a gem of an offspring. Your Father has you close to his heart. May he rest in peace

j-o-h-n Friday 12/24/2021 6:01 PM EST - Happy Christ's birthday tomorrow.

Magnus1964 profile image
Magnus1964

We are all saddened by your loss.

noahware profile image
noahware

Sorry for your loss. The question you ask is tough to answer, because it really varies from man to man. If one is younger, very active, and otherwise healthy (and willing and able to do enough weight-bearing exercises) then the loss of androgens may not impact health as quickly or severely as for someone already older, sicker and/or sedentary. Mental health is obviously also a huge wild card. But yes, to some degree the hormone therapy is itself a form of accelerated aging.

Joecarver profile image
Joecarver in reply to noahware

You got that right, at 80yrs old already started downhill prior to dx.

Yep that describes it pretty accurately. Accelerated aging

Sandy752 profile image
Sandy752

Good question but as noahware said the answer varies from man to man. I'm almost 77 and have been on Lupron close to 8 years. I've maintained my weight, walk 2-3 miles each day and do light weights most days.

Jp2sea profile image
Jp2sea

So sorry. The treatment we endure takes a toll. I'm not yet 50 but I expect my life will be condensed. Of course, we all have limited time on this blue planet, and we must celebrate with family and friends and their member. May you and all find joy during this holiday season.

msnik profile image
msnik

hello, I am so sorry to hear of your loss of your father. I just looked at a couple of yourprevious postings here. I think you can look for some comfort in the fact that you tried

to help him as well as you could by educating yourself about treatments and reaching out for advice. I am sorry about the losses he suffered before his death in terms of his strength. I suspect there are a lot of men here who understand what you are describing. I hope you have friends or family to help support you at this difficult time. take care.

Pancake_Lefse profile image
Pancake_Lefse

So sorry for your incredible loss. Deepest sympathies.

Lettuce231 profile image
Lettuce231

Androgeen, I am so sorry for you and your family, such a tragic loss.

You have asked an excellent question, maybe the type of question some of us wouldn't want to know the answer too.

I'm now 65 years old, my first elevated PSA reading was 103, ten years ago next year. The doctor didn't follow up and sometime later after approaching another doctor I got the news.

I've been on various treatments since and I have increased my stamina from the initial blast of treatment. But the frustration of not being as strong as I was, the changes to my mind and body annoy me beyond belief.

My dog Beau was a pup at the time, just a few minutes ago he " helped " me to wrap my wife's Christmas present. I didn't expect to see him grow up.

Hence the reason why I say, personally I'd rather not know if there are limits to our endurance, it never ceases to amaze me the amount of determination the guys show on here.

We send you our love.

Hailwood profile image
Hailwood

Condolences to you and your family. I see that in my mind and body on the hormones, but to keep the cancer away, its a fight that we must endure. Your support and love for your father will have been equal to any medications he was taking.

London441 profile image
London441

I’m very sorry for your loss. It is indeed a cruel reality that hormone deprivation is, in so many cases, the only option for extending life.

It’s true that those who are stronger and fitter when they begin ADT enjoy better quality of life on it, but not necessarily longer, and it’s only better relatively.

It’s a really difficult commitment to do what’s needed to ‘endure’ it, as you say. And this is in the best of conditions. The ones that tell you it accelerates age are correct. All the calamities of normal aging arrive sooner, and consistent intense cardiovascular and strength training (along with caloric restriction) are our only effective defense.

Eventually though, for many of us it simply doesn’t feel worth it anymore. Sadly this happens very soon after starting treatment for too many.

It’s also true that every man is different. This means not only differing abilities to tolerate the drugs, but widely varying differences in how long they work.

We can in the near future reasonably expect breakthroughs that will enable us to put ADT behind us, as with so many other drugs. Until then we have these.

Some men simply refuse to take them at all, such is the amount of negative information about them. Life without testosterone is unbearable for some. This has not been my experience, but I sympathize with it.

Don’t look back any more than you feel you have to. Again, I’m so sorry you had to witness this.

Realistic profile image
Realistic

How heartbreaking for you so sorry for your sad loss . Condolences SheilaFx

Horse12888 profile image
Horse12888

So sorry for your loss.

Grief and anger are an extremely common response to this disease, and especially its treatment. When I was on ADT and realized how shitty I felt every second of every day, that my sex life was over, etc., my emotions vacillated between uncontrollable tears and desperately wanting to kill someone, because of how completely unfair it was that I, though totally innocent, should be punished like this.

Over time, however, I was able to put the past behind me and move on with my life. I hope in earnest that you can do the same.

As others have said, there are no good answers here.

j-o-h-n profile image
j-o-h-n

Your dear Dad is finally resting peacefully. He will be with you every day showering his love on you and your family. God Bless Him...

j-o-h-n Friday 12/24/2021 5:56 PM EST - Happy Christ's birthday tomorrow.

1waserefornow profile image
1waserefornow

Read your post and my heart went out to you and your family…My son passed away a month ago, that once strong powerful muscular man dwindled to a shadow of his former self, heartbreaking to witness and second round of chemo finished him off. Hanging onto the resurrection hope and we can hold him in our arms again, praying the same for you and yours.

jfoesq profile image
jfoesq

I am sorry for your loss. FYI- I started Lupron 9+ years ago. I had 3 vacations and started Zytiga early on. Treatment is still effective for me. Having said that- I added 15 pounds from HS til my ex 37 years later. After starting Lupron, I added 15 pounds in 6 weeks and 5 more shortly thereafter. I have no sex drive, have lost muscle mass among other side effects. So- the side effects are unpleasant for sure-

BUT- I am happy to suffer them if the treatment keeps me around.

Poowater profile image
Poowater

Sincere condolences for your great loss.

Every man is different. I'm 78, going on 79. Had radical prostatectom,y 2017, two lots radiation, and chemo. I'm on Zoladex, Zytiga, and Denusomab for bones. Went from 68 PSA to non detectable, now. The only side effect is mild hot flushes. I'm able to run, and do exercise 7 days a week, including many sessions of resistance training. I feel normal.

Spyder54 profile image
Spyder54

So sorry for the loss of your Father. Yes, this triple blockade of ADT is tough on our bodies. Some men can take it for 10+ years. I am Only 13 mos in at age 67 and everything has changed but I try to extend life, so I keep after it. Hang in, your Fathers spirit will be with you often. You will remember expressions and mannerisms that will come to you.

Mike

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