Erleada (Apalutamide)

[Rberke]

Does anyone else take Apalutamide? Combined with Lupron has worked but side affects continuing for over a year has me clamoring for a break. Cancer had spread to bones but PSA <0.01.

Want to try a break but DR. indicates once I stop, cannot go back on above- Any Thoughts?

Richard

[MJCA]

Hi I have been on my holy trinity of Erleada, Lupron and Xgeva going on 3 years. I still have depression, it is not as bad as it was initially. The same goes for my limited appetite and nausea. Are you experiencing anything else?

[Boywonder56]

Ive been in titan trial over 4 yrs so lupron / erleada since dx w stg 4 gl9 ductal hystoligy pinv. And side effects are for me a mofo....fatigue a biggie and muscle bone loss....i was told from gitgo no vac....but i am seriously rethinking....i would have to give up the 16k worth of erleada ...but my psa has justnow gotten to .06.....so...i dont know...but i do believe the combo has kept me going longer than the max 2yrs at dx if i did nothing

[Chadsdad]

2 years for me on Eligard/Erleada and Prolia. 0 PSA for that time with T level <4. Hot flushes, fatigue, muscle loss and don’t sleep well most nights. If it gets no worse, I can stand it for another 20 years. Would love a vacation, just don’t won’t this stuff to wake up. There are trials that are adding a chemo drug to similar regimen that I’m researching. Right now I’m NED.

[Hailwood]

It is almost a year now on Lupron q4months and Erleada 240mg a day. Usual effects of fatigue, muscle loss, slight moob enlargement and a kind of couch potato figure despite limiting my intake. For me, its kind of a waiting game, especially with the high incidence of cardiac issues in the background, and of course the hesitation prior to the next blood test (Jan 4th) to see if PSA/T are rising. I still work full time and I think I am having some mild memory issues, or am I?😀😀😀

[spotsdad]

I was on Erleada and had all the usual SEs, brain fog, weakness, etc. I put up with all that, then I developed the "Erleada Rash". They call it a rash but it is far worse than any rash I have ever had - rough red "alligator"skin and severe itching. Couldn't even wear a shirt for months, stopped Erleada and it slowly cleared up. Went back on it at my DR's urging and the rash started again so I quit, it was horrible - no QOL. Now I'm on Xtandi and life is much better.

[Shooter1 in reply to spotsdad]

Xtandi made me a complete invalid. Cut to 80 mg and I'm 4 1/2 years with one hickup. If 160 mg is to much, cut it.

[Boywonder56 in reply to Shooter1]

What i really notice to on lupron / erleada...scratches and cuts take a lot longer to heal and all get redness around them....i work on my own cars and still do a little cinstruction work...

[j-o-h-n]

Stay the course........... golf one too.............

Good Luck, Good Health and Good Humor

j-o-h-n Wednesday 12/22/2021 6:45 PM EST