I’m currently taking 5mg prednisone daily along with my 1000mg abiraterone. I’ve noticed that my blood pressure has been creeping up… averaging maybe 140/80. Is this a case where I would maybe be a candidate for 10 mg of prednisone instead of just 5mg? I see my oncologist next week and plan on asking but wondered what other people are taking that are on this treatment plan (3 mo Lupron as well). Thanks!
Zytiga and Prednisone dosage - Advanced Prostate...
Check potassium levels.
Interesting that you say that TA. Why? Not to hijack this post, but my potassium is down to 3.2 and Scholz wants me to double up to 10mg prednisone. Does that make sense? Are you concerned that bean1008 might get too high a potassium level?
No, too low. Hypokalemia can arise from not taking enough prednisone with Zytiga. Low potassium, high BP and edema can result.
You’re right. Mine is too low. Bp good tho. They doubled me up to 10mg and lots of bananas etc.
Now watch those bananas..... Warning: don't put them in the frig............ Leaves no room for the beer............
Good Luck, Good Health and Good Humor.
j-o-h-n Thursday 10/28/2021 6:40 PM DST
Goof point. I think beer has more potassium than bananas anyway.
My potassium is 4.8 so I think that’s a good number.
Yes, so prednisone isn't the issue. Your BP isn't that high - possibly control with diet, exercise, no smoking, meditation, etc.?
I was on Zytiga for 8 months as part of a clinical trial. I had 10 mg Prednisone with it.
10mg pred is the normal dose. 5mg is just the starting dose.
My BP was climbing, we added 25mg losaetan and it seems to have helped. Blood sugar was also rising. We cut prednisone from 10mg to 5 amd rhat had a positive effect on lowering blood sugar.
My husband is on half dose of abiraterone (along with full dose of darolutamide) and told he would not need prednisone until/unless he goes full dose abi.
He had an early morning cortisol test ordered by his endocrinologist which came back low. That is a poor indication for adrenal gland. She asked him to start the 5 mg of prednisone and to inform his oncologist of the situation. She said it would make my husband feel better. He says he already feels great.
His blood pressure has been slightly elevated but at his age slightly high is better for fall prevention.
We were on Zytiga for 2 1/2 years. Took 5 mg prednisone twice a day. Around a year and a half to two years in his blood pressure went up as well. He was on high blood pressure med until we got off of the Zytiga. Then it returned to normal.
My BP slowly rose when I as on Zytiga/Prednisone. When I brought it to the attention of my MO they put me on Amlodipine 5 mg/day. Am now on Xtandi and am still on the BP med and monitoring it at home. 140-150's in the AM and 110-120's in the evening. I find that hydration is key to controlling it.
All the Best, Tom
My Doctor cut me down to 750mg. Zytiga and one 5mg. Prednisone in the morning with Breakfast, one half pill at Dinner. That was three years ago and all my numbers have been good including BP. PSA steady at 0.1 Never give up Never surrender. Leo
Good to know, Leo! I wondered if we might tinker a bit with my Zytiga dosage!
Please don't tinker ask your Doctor first. I'm sure you know by now we are all different as is our Cancers. It's worth talking to him about. Good luck.
Goodness no! I wouldn’t dream of doing that! 😳
Again my dosage is and has been for over three years now. Three Zytiga 750 mg. On an empty stomach early AM: one Prendisone 5mg with Breakfast ,one half Prendisone with dinner. I also take Calcium, Vitamin D,Fish oil pills,and Magnesium supplements. By Doctor advice. I hope this helps all my numbers returned to normal and PSA is 0.1 Leo