Started chemo after abiraterone failu... - Advanced Prostate...

Advanced Prostate Cancer

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Started chemo after abiraterone failure-need help!!!

Vsahay profile image
14 Replies

Hello everyone

My father got his 1 st docetaxel infusion on 30th sep.

He is getting lower back pain associated with bone mets for nearly 15 days.

Will chemo help with the pain ?

How long will it take to get some relief from the pain?

Has anyone got a good response in mCRPC with docetaxel after failing abiraterone?

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Vsahay profile image
Vsahay
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14 Replies
Tall_Allen profile image
Tall_Allen

Yes, pain flares are very common when starting chemo or radiation. His MO may want to increase the dose of prednisone for a week or two.

Vsahay profile image
Vsahay in reply to Tall_Allen

Can chemo cause urinary incontinence?Since he took chemo, he has urge to go to washroom every half an hour .Also wetting bed at night

Tall_Allen profile image
Tall_Allen in reply to Vsahay

Never heard that - ask his oncologist.

docbulldog profile image
docbulldog in reply to Vsahay

I had more trouble with urinary incontinence when I was on Zytiga and Prednisone. Since I’ve started Chemotherapy that is controlled. Biggest side effect with Docetaxel after 4 infusions has been swelling in my lower legs and feet and more neuropathy and plain feeling weak.Hoping he does well on his infusions.

Vsahay profile image
Vsahay in reply to docbulldog

Thanks

Boywonder56 profile image
Boywonder56

Yes ta is correct the bone paine flare i got from start of adt was almost suicidal..but did decrease to nill....

Vsahay profile image
Vsahay in reply to Boywonder56

Thanks

Olivia007 profile image
Olivia007

Did he have the bone pain before the treatment or after?

Vsahay profile image
Vsahay in reply to Olivia007

He was having bone pain since 10 days before treatment and it is still there.

Olivia007 profile image
Olivia007 in reply to Vsahay

That’s what I thought u meant some people on the forum made it sound like the chemo started his pain but u said he had it before the chemo. I’m not sure if it will help with his pain? My dad has prostate cancer and bone Mets for 7 years now he hasn’t tried chemo yet he is on xtandi but it hasn’t helped with bone pain it’s to keep the PSA low my dad did have radiation on his bone Mets and the doctors all claimed it will alleviate the bone pain and my dad said he saw no relief and that his skin feels like it’s still burning this was a year ago if u see your dad gets relief with chemo let me know. My dad feels like there is no relief just promises or false hope

Scribb profile image
Scribb

I was on oxycodone for severe back pain caused by the compressive effects of an L1 spinal tumor. My MO put me on Docetaxel in the hope that it would shrink the tumor and treat my other mets systemically. In the meantime, I consulted a palliative care physician at another institution. He recommended interrupting chemo and targeting the problem tumor with radiation for palliative purposes. My MO agreed with his recommendation. My back pain subsided within a week of completing the radiation treatments (3 consecutive days) and I was able to discontinue oxycodone (the withdrawal was not fun!). I have since had my second chemo infusion and my PSA (now around 3.0) has begun to fall. Apparently every patient responds differently but I am glad I sought a second opinion.

Vsahay profile image
Vsahay in reply to Scribb

Did you have any side effects from radiation?

wpopomaronis profile image
wpopomaronis

First let me say that this medicine did help decrease my PSA. My tumors were growing quickly and the drug kept them at bay. But there is a price to pay for all of us. The drug gave me peripheral neuropathy in my feed that remains today two years later. It also decreases the white blood cells and even though they give you a stimulant I got a septicemia made up of fungal and bacteria. Was hospitalized for five days and by the grace of God lived. I think part of the way you will experience side effects is based on the current health and stamina of the individual. They gave me a drug called Neulasta to increase my white blood cell counts and it felt like somebody was hitting me with a rubber but all over my body. I did not have nausea, urinary incontinence or constipation. In closing it may help you and depending on the choices you have left you may want to consider it. Good luck to you sir!

Vsahay profile image
Vsahay in reply to wpopomaronis

Thanks for the good wishes!I wish the treatment works well for my father too.

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